*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : OP4100000
CHEMICAL NAME           : beta-D-Mannopyranoside,
                          O-4-C-(1-methoxyethyl)-2,3-O-methylenepentopyranosyli
                          dene-
                          (1-3-4)-2-O-methyl-alpha-L-lyxopyranosyl-O-2,3,6-trid
                          eoxy-3-C-methyl-4-O-m ethyl-3-nitro-
                          alpha-L-arabino-hexopyranosyl-(1-3)-O-2,6-dideoxy-4-O
                          -(3,5-dichloro-4-hydr oxy-2-methoxy-
                          6-methylbenzoyl)-beta-D-arabino-hexopyranosyl-(1-4)-O
                          -2,6-dideoxy-D-ribo-h exopyranosylidene-
                          (1-3-4)-O-2,6-dideoxy-3-C-methyl-beta-D-arabino-hexop
                          yranosyl-(1-3)-O-6-de oxy-4-O-methyl-
                          beta-D-galactopyranosyl-(1-4)-2,6-di-O-methyl-
CAS REGISTRY NUMBER     : 39340-46-0
BEILSTEIN REFERENCE NO. : 1679197
LAST UPDATED            : 199612
DATA ITEMS CITED        : 4
MOLECULAR FORMULA       : C66-H99-Cl2-N-O35
MOLECULAR WEIGHT        : 1537.56
WISWESSER LINE NOTATION : QY1&1YQYVHOVR DQ CG EG B1 FO1
COMPOUND DESCRIPTOR     : Drug
                          Organometallic
                          Natural Product
SYNONYMS/TRADE NAMES :
   * Everninomicin D
 
                       *** HEALTH HAZARD DATA ***
 
                        ** ACUTE TOXICITY DATA **
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intramuscular
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : >400 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   AACHAX Antimicrobial Agents and Chemotherapy (1961-70).  (Ann Arbor, MI)
   1961-70.  For publisher information, see AMACCQ.  Volume(issue)/page/year:
   -,38,1964
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intravenous
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 125 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   AACHAX Antimicrobial Agents and Chemotherapy (1961-70).  (Ann Arbor, MI)
   1961-70.  For publisher information, see AMACCQ.  Volume(issue)/page/year:
   -,24,1964
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intramuscular
SPECIES OBSERVED        : Mammal - dog
DOSE/DURATION           : >140 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   AACHAX Antimicrobial Agents and Chemotherapy (1961-70).  (Ann Arbor, MI)
   1961-70.  For publisher information, see AMACCQ.  Volume(issue)/page/year:
   -,38,1964
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intramuscular
SPECIES OBSERVED        : Rodent - rabbit
DOSE/DURATION           : >300 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   AACHAX Antimicrobial Agents and Chemotherapy (1961-70).  (Ann Arbor, MI)
   1961-70.  For publisher information, see AMACCQ.  Volume(issue)/page/year:
   -,38,1964
 
                            *** END OF RECORD ***