*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : OQ2293000
CHEMICAL NAME           : Maytansine,
                          3-de(2-(acetylmethylamino)propionyloxy)-3-hydroxy-,
                          butyrate (ester)
CAS REGISTRY NUMBER     : 66547-09-9
LAST UPDATED            : 199401
DATA ITEMS CITED        : 1
MOLECULAR FORMULA       : C32-H43-Cl-N2-O9
MOLECULAR WEIGHT        : 635.22
COMPOUND DESCRIPTOR     : Drug
                          Natural Product
SYNONYMS/TRADE NAMES :
   * Ansamitocin P-3'
   * Antibiotic C 15003P3'
   * C 15003 P-3'
   * 3-De(2-(acetylmethylamino)propionyloxy)-3-hydroxymaytansine butyrate  
   (ester)
   * Maytansine, O(sup 3)-de(2-(acetylmethylamino)-1-oxopropyl)-O(sup  
   3)-(1-oxobutyl)-
   * Maytansinol butyrate
 
                       *** HEALTH HAZARD DATA ***
 
                        ** ACUTE TOXICITY DATA **
 
TYPE OF TEST            : LDLo - Lowest published lethal dose
ROUTE OF EXPOSURE       : Intraperitoneal
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 625 ug/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   JKXXAF Japanese Kokai Tokyo Koho Patents.  (U.S. Patent and Trademark
   Office, Foreign Patents, Washington, DC 20231)  Volume(issue)/page/year:
   #78-130495
 
                            *** END OF RECORD ***