*** CHEMICAL IDENTIFICATION *** RTECS NUMBER : OS9542200 CHEMICAL NAME : p-Menthan-3-one, trans- CAS REGISTRY NUMBER : 89-80-5 LAST UPDATED : 199701 DATA ITEMS CITED : 6 MOLECULAR FORMULA : C10-H18-O MOLECULAR WEIGHT : 154.28 WISWESSER LINE NOTATION : L6VTJ BY1&1 E1 COMPOUND DESCRIPTOR : Mutagen SYNONYMS/TRADE NAMES : * Cyclohexanone, 5-methyl-2-(1-methylethyl)-, trans- * Menthone * p-Menthone * trans-Menthone *** HEALTH HAZARD DATA *** ** ACUTE TOXICITY DATA ** TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Oral SPECIES OBSERVED : Rodent - rat DOSE/DURATION : 500 mg/kg TOXIC EFFECTS : Details of toxic effects not reported other than lethal dose value REFERENCE : FRXXBL French Demande Patent Document. (U.S. Patent and Trademark Office, Foreign Patents, Washington, DC 20231) Volume(issue)/page/year: #2448856 TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Subcutaneous SPECIES OBSERVED : Rodent - mouse DOSE/DURATION : 2180 mg/kg TOXIC EFFECTS : Behavioral - anticonvulsant Behavioral - sleep REFERENCE : JAPMA8 Journal of the American Pharmaceutical Association, Scientific Edition. (Washington, DC) V.29-49, 1940-60. For publisher information, see JPMSAE. Volume(issue)/page/year: 46,77,1957 TYPE OF TEST : LDLo - Lowest published lethal dose ROUTE OF EXPOSURE : Intravenous SPECIES OBSERVED : Mammal - dog DOSE/DURATION : 600 mg/kg TOXIC EFFECTS : Cardiac - change in rate Vascular - BP lowering not characterized in autonomic section REFERENCE : COREAF Comptes Rendus Hebdomadaires des Seances, Academie des Sciences. (Paris, France) V.1-261, 1835-1965. For publisher information, see CRASEV. Volume(issue)/page/year: 236,633,1953 ** MUTATION DATA ** TYPE OF TEST : Mutation in microorganisms TEST SYSTEM : Bacteria - Salmonella typhimurium DOSE/DURATION : 6400 ng/plate REFERENCE : MUREAV Mutation Research. (Elsevier Science Pub. B.V., POB 211, 1000 AE Amsterdam, Netherlands) V.1- 1964- Volume(issue)/page/year: 138,17,1984 *** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA *** NIOSH OCCUPATIONAL EXPOSURE SURVEY DATA : NOHS - National Occupational Hazard Survey (1974) NOHS Hazard Code - T0386 No. of Facilities: 18 (estimated) No. of Industries: 1 No. of Occupations: 13 No. of Employees: 3245 (estimated) *** STATUS IN U.S. *** EPA TSCA Section 8(b) CHEMICAL INVENTORY *** END OF RECORD ***