*** CHEMICAL IDENTIFICATION ***
RTECS NUMBER : OV6475000
CHEMICAL NAME : Mercury, (acetato)phenyl-
CAS REGISTRY NUMBER : 62-38-4
OTHER CAS REGISTRY NOS. : 61840-45-7
1337-06-0
64684-45-3
LAST UPDATED : 199712
DATA ITEMS CITED : 63
MOLECULAR FORMULA : C8-H8-Hg-O2
MOLECULAR WEIGHT : 336.75
WISWESSER LINE NOTATION : 1VO-HG-R
COMPOUND DESCRIPTOR : Agricultural Chemical
Tumorigen
Organometallic
Mutagen
Reproductive Effector
Primary Irritant
SYNONYMS/TRADE NAMES :
* Acetate phenylmercurique
* (Acetato)phenylmercury
* Acetic acid, phenylmercury deriv.
* (Acetoxymercuri)benzene
* Acetoxyphenylmercury
* Algimycin 200
* Anticon
* Antimucin WBR
* Antimucin WDR
* Benzene, (acetoxymercuri)-
* Bufen
* Bufen 30
* Ceresol
* Contra Creme
* Dyanacide
* Femma
* Fenylmerkuriacetat
* Fungicide R
* Fungitox OR
* Hexasan
* Hexasan (fungicide)
* Intercide 60
* Intercide PMA 18
* Liquiphene
* Lorophyn
* Mercuriphenyl acetate
* Mercuron
* Mercury (II) acetate, phenyl-
* Mercury, acetoxyphenyl-
* Mergal A 25
* Mersolite D
* Mersolite 8
* Neantina
* Norforms
* Nuodex PMA 18
* Nylmerate
* Octan fenylrtutnaty
* Panomatic
* Phenomercuric acetate
* Phenylmercuriacetate
* Phenyl mercuric acetate
* Phenylmercury acetate
* Phenylmercury(II) acetate
* Phenylquecksilberacetat
* Phix
* PMA (fungicide)
* PMAC
* PMAS
* Programin
* Purasan-SC-10
* Puraturf 10
* Quicksan
* Quicksan 20
* RCRA waste number P092
* Ruberon
* Samtol
* Sanitized SPG
* Scutl
* Seed Dressing R
* Seedtox
* Setrete
* Shimmerex
* Spor-Kil
* Spruce Seal
* Tag
* Tag 331
* Tag fungicide
* Tag HL 331
* Trigosan
* Troysan 30
* Troysan PMA 30
* Verdasan
* Volpar
* Zaprawa Nasienna R
* Ziarnik
*** HEALTH HAZARD DATA ***
** SKIN/EYE IRRITATION DATA **
TYPE OF TEST : Standard Draize test
ROUTE OF EXPOSURE : Administration onto the skin
SPECIES OBSERVED : Human
DOSE/DURATION : 100 ug/24H
REACTION SEVERITY : Severe
REFERENCE :
ARDEAC Archives of Dermatology. (AMA, 535 N. Dearborn St., Chicago, IL
60610) V.82- 1960- Volume(issue)/page/year: 106,129,1972
TYPE OF TEST : Standard Draize test
ROUTE OF EXPOSURE : Administration into the eye
SPECIES OBSERVED : Rodent - rabbit
DOSE/DURATION : 50 ug/24H
REACTION SEVERITY : Severe
REFERENCE :
85JCAE "Prehled Prumyslove Toxikologie; Organicke Latky," Marhold, J.,
Prague, Czechoslovakia, Avicenum, 1986 Volume(issue)/page/year: -,1205,1986
** ACUTE TOXICITY DATA **
TYPE OF TEST : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE : Oral
SPECIES OBSERVED : Rodent - rat
DOSE/DURATION : 41 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
ATDAEI Acute Toxicity Data. Journal of the American College of Toxicology,
Part B. (Mary Ann Liebert, Inc., 1651 Third Ave., New York, NY 10128) V.1-
1990- Volume(issue)/page/year: 1,175,1992
TYPE OF TEST : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE : Oral
SPECIES OBSERVED : Rodent - mouse
DOSE/DURATION : 13250 ug/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
YAKUD5 Gekkan Yakuji. Pharmaceuticals Monthly. (Yakugyo Jihosha, Inaoka
Bldg., 2-36 Jinbo-cho, Kanda, Chiyoda-ku, Tokyo 101, Japan) V.1- 1959-
Volume(issue)/page/year: 22,291,1980
TYPE OF TEST : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE : Intraperitoneal
SPECIES OBSERVED : Rodent - mouse
DOSE/DURATION : 13 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
AMSVAZ Acta Medica Scandinavica. (Almqvist & Wiksell, POB 45150, S-10430
Stockholm, Sweden) V.52-224, 1919-88. Volume(issue)/page/year: 143,365,1952
TYPE OF TEST : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE : Subcutaneous
SPECIES OBSERVED : Rodent - mouse
DOSE/DURATION : 12 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
TOIZAG Toho Igakkai Zasshi. Journal of Medical Society of Toho University.
(Toho Daigaku Igakkai, 21-16, Omori-nishi, 5-chome, Ota-ku, Tokyo 143,
Japan) V.1- 1954- Volume(issue)/page/year: 9,101,1962
TYPE OF TEST : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE : Intravenous
SPECIES OBSERVED : Rodent - mouse
DOSE/DURATION : 18 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
CSLNX* U.S. Army Armament Research & Development Command, Chemical Systems
Laboratory, NIOSH Exchange Chemicals. (Aberdeen Proving Ground, MD 21010)
Volume(issue)/page/year: NX#00921
TYPE OF TEST : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE : Oral
SPECIES OBSERVED : Bird - chicken
DOSE/DURATION : 60 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
TXAPA9 Toxicology and Applied Pharmacology. (Academic Press, Inc., 1 E.
First St., Duluth, MN 55802) V.1- 1959- Volume(issue)/page/year:
2,344,1960
TYPE OF TEST : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE : Oral
SPECIES OBSERVED : Bird - quail
DOSE/DURATION : 71 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
AXVMAW Archiv fuer Experimentelle Veterinaermedizin. (S. Hirzel Verlag,
Postfach 506, Leipzig DDR-7010, Ger. Dem. Rep.) V.6- 1952-
Volume(issue)/page/year: 34,383,1980
TYPE OF TEST : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE : Intraperitoneal
SPECIES OBSERVED : Mammal - species unspecified
DOSE/DURATION : 10 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
TXCYAC Toxicology. (Elsevier Scientific Pub. Ireland, Ltd., POB 85,
Limerick, Ireland) V.1- 1973- Volume(issue)/page/year: 6,281,1976
TYPE OF TEST : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE : Unreported
SPECIES OBSERVED : Mammal - species unspecified
DOSE/DURATION : 17 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
30ZDA9 "Chemistry of Pesticides," Melnikov, N.N., New York, Springer-Verlag
New York, Inc., 1971 Volume(issue)/page/year: -,295,1971
** OTHER MULTIPLE DOSE TOXICITY DATA **
TYPE OF TEST : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE : Oral
SPECIES OBSERVED : Rodent - rat
DOSE/DURATION : 91 mg/kg/13W-C
TOXIC EFFECTS :
Kidney, Ureter, Bladder - changes in tubules (including acute renal failure,
acute tubular necrosis)
Biochemical - Enzyme inhibition, induction, or change in blood or tissue
levels - phosphatases
Biochemical - Enzyme inhibition, induction, or change in blood or tissue
levels - other Enzymes
REFERENCE :
ATSUDG Archives of Toxicology, Supplement. (Springer-Verlag New York, Inc.,
Service Center, 44 Hartz Way, Secaucus, NJ 07094) No.1- 1978-
Volume(issue)/page/year: 4,201,1980
TYPE OF TEST : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE : Oral
SPECIES OBSERVED : Rodent - rat
DOSE/DURATION : 346 mg/kg/1Y-C
TOXIC EFFECTS :
Kidney, Ureter, Bladder - changes in tubules (including acute renal failure,
acute tubular necrosis)
REFERENCE :
AMIHBC AMA Archives of Industrial Hygiene and Occupational Medicine.
(Chicago, IL) V.2-10, 1950-54. For publisher information, see AEHLAU.
Volume(issue)/page/year: 2,433,1950
** REPRODUCTIVE DATA **
TYPE OF TEST : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE : Oral
SPECIES OBSERVED : Rodent - rat
DOSE : 15 mg/kg
SEX/DURATION : female 6-10 day(s) after conception
TOXIC EFFECTS :
Reproductive - Effects on Embryo or Fetus - fetotoxicity (except death,
e.g., stunted fetus)
Reproductive - Specific Developmental Abnormalities - homeostasis
Reproductive - Specific Developmental Abnormalities - other developmental
abnormalities
REFERENCE :
PARWAC Polskie Archiwum Weterynaryjne. Polish Archives of Veterinary
Medicine. (Panstwowe Wydawnictwo Naukowe, POB 391, 00251 Warsaw, Poland)
V.1- 1951- Volume(issue)/page/year: 22,263,1980
TYPE OF TEST : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE : Subcutaneous
SPECIES OBSERVED : Rodent - mouse
DOSE : 110 ug/kg
SEX/DURATION : female 8 day(s) after conception
TOXIC EFFECTS :
Reproductive - Effects on Embryo or Fetus - fetal death
REFERENCE :
ARINAU Annual Report of the Research Institute of Environmental Medicine,
Nagoya University. (Nagoya, Japan) V.1-25, 1951-80.
Volume(issue)/page/year: 3,88,1956
TYPE OF TEST : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE : Intravaginal
SPECIES OBSERVED : Rodent - mouse
DOSE : 110 ug/kg
SEX/DURATION : female 7 day(s) after conception
TOXIC EFFECTS :
Reproductive - Effects on Embryo or Fetus - fetal death
Reproductive - Specific Developmental Abnormalities - musculoskeletal system
REFERENCE :
ARINAU Annual Report of the Research Institute of Environmental Medicine,
Nagoya University. (Nagoya, Japan) V.1-25, 1951-80.
Volume(issue)/page/year: 3,88,1956
TYPE OF TEST : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE : Oral
SPECIES OBSERVED : Rodent - rabbit
DOSE : 9 mg/kg
SEX/DURATION : female 8-12 day(s) after conception
TOXIC EFFECTS :
Reproductive - Effects on Embryo or Fetus - fetotoxicity (except death,
e.g., stunted fetus)
Reproductive - Specific Developmental Abnormalities - homeostasis
Reproductive - Specific Developmental Abnormalities - other developmental
abnormalities
REFERENCE :
PARWAC Polskie Archiwum Weterynaryjne. Polish Archives of Veterinary
Medicine. (Panstwowe Wydawnictwo Naukowe, POB 391, 00251 Warsaw, Poland)
V.1- 1951- Volume(issue)/page/year: 22,263,1980
TYPE OF TEST : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE : Oral
SPECIES OBSERVED : Rodent - hamster
DOSE : 20 mg/kg
SEX/DURATION : female 5 day(s) after conception
TOXIC EFFECTS :
Reproductive - Effects on Embryo or Fetus - fetotoxicity (except death,
e.g., stunted fetus)
REFERENCE :
PARWAC Polskie Archiwum Weterynaryjne. Polish Archives of Veterinary
Medicine. (Panstwowe Wydawnictwo Naukowe, POB 391, 00251 Warsaw, Poland)
V.1- 1951- Volume(issue)/page/year: 22,263,1980
TYPE OF TEST : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE : Intravenous
SPECIES OBSERVED : Rodent - hamster
DOSE : 7500 ug/kg
SEX/DURATION : female 8 day(s) after conception
TOXIC EFFECTS :
Reproductive - Fertility - post-implantation mortality (e.g. dead and/or
resorbed implants per total number of implants)
Reproductive - Effects on Embryo or Fetus - fetotoxicity (except death,
e.g., stunted fetus)
Reproductive - Specific Developmental Abnormalities - homeostasis
REFERENCE :
LSBGAY Life Sciences, Part 2: Biochemistry, General and Molecular Biology.
(New York, NY) V.9-13, 1970-73. For publisher information, see LIFSAK.
Volume(issue)/page/year: 10,1341,1971
TYPE OF TEST : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE : Intravenous
SPECIES OBSERVED : Rodent - hamster
DOSE : 8 mg/kg
SEX/DURATION : female 8 day(s) after conception
TOXIC EFFECTS :
Reproductive - Specific Developmental Abnormalities - Central Nervous System
REFERENCE :
LSBGAY Life Sciences, Part 2: Biochemistry, General and Molecular Biology.
(New York, NY) V.9-13, 1970-73. For publisher information, see LIFSAK.
Volume(issue)/page/year: 10,1341,1971
TYPE OF TEST : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE : Intraperitoneal
SPECIES OBSERVED : Mammal - species unspecified
DOSE : 125 ug/kg
SEX/DURATION : female 8 day(s) after conception
TOXIC EFFECTS :
Reproductive - Fertility - post-implantation mortality (e.g. dead and/or
resorbed implants per total number of implants)
REFERENCE :
TXCYAC Toxicology. (Elsevier Scientific Pub. Ireland, Ltd., POB 85,
Limerick, Ireland) V.1- 1973- Volume(issue)/page/year: 6,281,1976
** MUTATION DATA **
TYPE OF TEST : DNA repair
TEST SYSTEM : Bacteria - Escherichia coli
DOSE/DURATION : 2 mmol/L
REFERENCE :
MJDHDW Mukogawa Joshi Daigaku Kiyo, Shokumotsu-hen. Bulletin of Mukogawa
Women's University, Food Science Series. (Mukogawa Joshi Daigaku, 6-46,
Ikebiraki-cho, Nishinomiya, Hyogo-ken, Japan) No.19- 1972-
Volume(issue)/page/year: 28,F39,1980
TYPE OF TEST : DNA repair
TEST SYSTEM : Bacteria - Bacillus subtilis
DOSE/DURATION : 50 mmol/L
REFERENCE :
MUREAV Mutation Research. (Elsevier Science Pub. B.V., POB 211, 1000 AE
Amsterdam, Netherlands) V.1- 1964- Volume(issue)/page/year: 31,185,1975
TYPE OF TEST : DNA repair
TEST SYSTEM : Bacteria - Bacillus subtilis
DOSE/DURATION : 1 mmol/L
REFERENCE :
MUREAV Mutation Research. (Elsevier Science Pub. B.V., POB 211, 1000 AE
Amsterdam, Netherlands) V.1- 1964- Volume(issue)/page/year: 77,109,1980
TYPE OF TEST : Sex chromosome loss and nondisjunction
ROUTE OF EXPOSURE : Oral
TEST SYSTEM : Insect - Drosophila melanogaster
DOSE/DURATION : 200 ppm
REFERENCE :
ENVRAL Environmental Research. (Academic Press, Inc., 1 E. First St.,
Duluth, MN 55802) V.1- 1967- Volume(issue)/page/year: 36,218,1985
TYPE OF TEST : Sister chromatid exchange
TEST SYSTEM : Human Lymphocyte
DOSE/DURATION : 30 mg/L
REFERENCE :
DBABEF Doga Bilim Dergisi, Seri A2: Biyoloji. Natural Science Journal,
Series A2. (Turkiye Bilimsel ve Teknik Arastirma Kurumu, Ataturk Bul. No.
221, Kavaklidere, Ankara, Turkey) V.8- 1984- Volume(issue)/page/year:
8,105,1984
TYPE OF TEST : DNA inhibition
TEST SYSTEM : Rodent - mouse Lymphocyte
DOSE/DURATION : 1 umol/L
REFERENCE :
BCPCA6 Biochemical Pharmacology. (Pergamon Press Inc., Maxwell House,
Fairview Park, Elmsford, NY 10523) V.1- 1958- Volume(issue)/page/year:
24,489,1975
TYPE OF TEST : Mutation test systems - not otherwise specified
TEST SYSTEM : Rodent - mouse Lymphocyte
DOSE/DURATION : 10 umol/L
REFERENCE :
BCPCA6 Biochemical Pharmacology. (Pergamon Press Inc., Maxwell House,
Fairview Park, Elmsford, NY 10523) V.1- 1958- Volume(issue)/page/year:
24,489,1975
TYPE OF TEST : Cytogenetic analysis
ROUTE OF EXPOSURE : Oral
TEST SYSTEM : Mammal - pig
DOSE/DURATION : 160 mg/kg/32D (Continuous)
REFERENCE :
VETNAL Veterinariya. Veterinary Science. (V/O Mezhdunarodnaya Kniga,
113095 Moscow, USSR) V.1- 1924- Volume(issue)/page/year: 52(8),91,1975
*** REVIEWS ***
ACGIH TLV-TWA 0.1 mg(Hg)/m3 (skin)
DTLVS* The Threshold Limit Values (TLVs) and Biological Exposure Indices
(BEIs) booklet issues by American Conference of Governmental Industrial
Hygienists (ACGIH), Cincinnati, OH, 1996 Volume(issue)/page/year:
TLV/BEI,1997
IARC Cancer Review:Human Inadequate Evidence
IMEMDT IARC Monographs on the Evaluation of Carcinogenic Risk of Chemicals
to Man. (WHO Publications Centre USA, 49 Sheridan Ave., Albany, NY 12210)
V.1- 1972- Volume(issue)/page/year: 58,239,1993
IARC Cancer Review:Group 2B
IMEMDT IARC Monographs on the Evaluation of Carcinogenic Risk of Chemicals
to Man. (WHO Publications Centre USA, 49 Sheridan Ave., Albany, NY 12210)
V.1- 1972- Volume(issue)/page/year: 58,239,1993
TOXICOLOGY REVIEW
AJOGAH American Journal of Obstetrics and Gynecology. (C.V. Mosby Co.,
11830 Westline Industrial Dr., St. Louis, MO 63146) V.1- 1920-
Volume(issue)/page/year: 126,390,1976
TOXICOLOGY REVIEW
SDGTB3 Seminars in Drug Treatment. (New York, NY) V.1-3, 1971-74.
Discontinued. Volume(issue)/page/year: 1,177,1971
TOXICOLOGY REVIEW
BIOGAL Biologico. (Instituto Biologica, Av. Cons. Rodriques Alves, 1252,
CEP 04014, Sao Paulo, Brazil) V.1- 1935- Volume(issue)/page/year:
41(7),208,1975
TOXICOLOGY REVIEW
ADTEAS Advances in Teratology. (New York, NY) V.1-5, 1966-72.
Discontinued. Volume(issue)/page/year: 5,51,1972
*** U.S. STANDARDS AND REGULATIONS ***
EPA FIFRA 1988 PESTICIDE SUBJECT TO REGISTRATION OR RE-REGISTRATION
FEREAC Federal Register. (U.S. Government Printing Office, Supt. of
Documents, Washington, DC 20402) V.1- 1936- Volume(issue)/page/year:
54,7740,1989
MSHA STANDARD-air:TWA 0.05 mg(Hg)/m3
DTLWS* "Documentation of the Threshold Limit Values for Substances in
Workroom Air," Supplements. For publisher information, see 85INA8.
Volume(issue)/page/year: 3,22,1973
*** OCCUPATIONAL EXPOSURE LIMITS ***
OEL-AUSTRALIA:TWA 0.05 mg(Hg)/m3;Skin JAN 1993
OEL-BELGIUM:TWA 0.05 mg(Hg)/m3;Skin JAN 1993
OEL-DENMARK:TWA 0.05 mg(Hg)/m3 JAN 1993
OEL-FINLAND:TWA 0.05 mg(Hg)/m3 JAN 1993
OEL-FRANCE:TWA 0.05 mg(Hg)/m3 JAN 1993
OEL-GERMANY:TWA 0.01 ppm (0.1 mg(Hg)/m3) JAN 1993
OEL-HUNGARY:TWA 0.02 mg(Hg)/m3;STEL 0.04 mg(Hg)/m3 JAN 1993
OEL-JAPAN:TWA 0.05 mg(Hg)/m3 JAN 1993
OEL-THE NETHERLANDS:TWA 0.05 mg(Hg)/m3;STEL 0.15 mg(Hg)/m3 JAN 1993
OEL-THE PHILIPPINES:TWA 0.05 mg(Hg)/m3 JAN 1993
OEL-POLAND:TWA 0.01 mg(Hg)/m3 JAN 1993
OEL-RUSSIA:TWA 0.05 mg(Hg)/m3;STEL 0.01 mg(Hg)/m3 JAN 1993
OEL-SWEDEN:TWA 0.05 mg(Hg)/m3 JAN 1993
OEL-THAILAND:STEL 0.05 mg(Hg)/m3 JAN 1993
OEL-UNITED KINGDOM:TWA 0.05 mg(Hg)/m3;STEL 0.15 mg(Hg)/m3 JAN 1993
OEL IN BULGARIA, COLOMBIA, JORDAN, KOREA check ACGIH TLV
OEL IN NEW ZEALAND, SINGAPORE, VIETNAM check ACGIH TLV
*** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA ***
NIOSH RECOMMENDED EXPOSURE LEVEL (REL) :
NIOSH REL TO MERCURY, ARYL AND INORGANIC-air:CL 0.1 mg/m3 (Sk)
REFERENCE :
NIOSH* National Institute for Occupational Safety and Health, U.S. Dept. of
Health, Education, and Welfare, Reports and Memoranda.
Volume(issue)/page/year: DHHS #92-100,1992
NIOSH OCCUPATIONAL EXPOSURE SURVEY DATA :
NOHS - National Occupational Hazard Survey (1974)
NOHS Hazard Code - 57340
No. of Facilities: 588 (estimated)
No. of Industries: 11
No. of Occupations: 29
No. of Employees: 10962 (estimated)
NOES - National Occupational Exposure Survey (1983)
NOES Hazard Code - 57340
No. of Facilities: 2429 (estimated)
No. of Industries: 27
No. of Occupations: 30
No. of Employees: 28342 (estimated)
No. of Female Employees: 5150 (estimated)
*** STATUS IN U.S. ***
EPA GENETOX PROGRAM 1988, Positive: D melanogaster-whole sex chrom. loss
EPA GENETOX PROGRAM 1988, Positive: D melanogaster-nondisjunction; B
subtilis rec assay
EPA TSCA Section 8(b) CHEMICAL INVENTORY
On EPA IRIS database
EPA TSCA TEST SUBMISSION (TSCATS) DATA BASE, JUNE 1998
*** END OF RECORD ***