*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : OW1050000
CHEMICAL NAME           : Mercury, chloro(2-methoxy-3-ureidopropyl)-
CAS REGISTRY NUMBER     : 62-37-3
LAST UPDATED            : 199712
DATA ITEMS CITED        : 24
MOLECULAR FORMULA       : C5-H11-Cl-Hg-N2-O2
MOLECULAR WEIGHT        : 367.22
WISWESSER LINE NOTATION : ZVM1YO1&1-HG-G
COMPOUND DESCRIPTOR     : Drug
                          Organometallic
SYNONYMS/TRADE NAMES :
   * (3-((Aminocarbonyl)amino)-2-methoxypropyl)chloromercury
   * Chlormerodrin
   * Chlormerodrine
   * Chlormeroprin
   * 1-(3-(Chloromercuri)-2-methoxypropyl)urea
   * Katonil
   * Mercardox
   * Mercloran
   * Mercury, (3-((aminocarbonyl)amino)-2-methoxypropyl-C1,O3)chloro-
   * Mercoral
   * Merculest
   * Merilid
   * Neohydrin
   * Oricur
   * Percapyl
   * Promeran
   * Urea, (3-(chloromercuri)-2-methoxypropyl)-
   * Urea, (2-methoxypropyl)-, mercury complex
 
                       *** HEALTH HAZARD DATA ***
 
                        ** ACUTE TOXICITY DATA **
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : 150 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   TXAPA9 Toxicology and Applied Pharmacology.  (Academic Press, Inc., 1 E.
   First St., Duluth, MN 55802) V.1-    1959-  Volume(issue)/page/year:
   18,185,1971
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 215 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   AIPTAK Archives Internationales de Pharmacodynamie et de Therapie. (Heymans
   Institute of Pharmacology, De Pintelaan 185, B-9000 Ghent, Belgium)  V.4-   
   1898-  Volume(issue)/page/year: 143,181,1963
 
TYPE OF TEST            : LDLo - Lowest published lethal dose
ROUTE OF EXPOSURE       : Intraperitoneal
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 62500 ug/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   CBCCT* "Summary Tables of Biological Tests," National Research Council
   Chemical-Biological Coordination Center.  (National Academy of Science
   Library, 2101 Constitution Ave., NW, Washington, DC 20418)
   Volume(issue)/page/year: 5,144,1953
 
TYPE OF TEST            : LDLo - Lowest published lethal dose
ROUTE OF EXPOSURE       : Subcutaneous
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 60 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   JAPMA8 Journal of the American Pharmaceutical Association, Scientific
   Edition.  (Washington, DC) V.29-49, 1940-60.  For publisher information, see
   JPMSAE.  Volume(issue)/page/year: 46,689,1957

                              *** REVIEWS ***
 
   ACGIH TLV-TWA 0.01 mg(Hg)/m3; STEL 0.03 mg/m3
   DTLVS* The Threshold Limit Values (TLVs) and Biological Exposure Indices
   (BEIs) booklet issues by American Conference of Governmental Industrial
   Hygienists (ACGIH), Cincinnati, OH, 1996  Volume(issue)/page/year:
   TLV/BEI,1997

                    *** U.S. STANDARDS AND REGULATIONS ***
 
   MSHA STANDARD-air:TWA 0.05 mg(Hg)/m3
   DTLWS* "Documentation of the Threshold Limit Values for Substances in
   Workroom Air," Supplements. For publisher information, see 85INA8.
   Volume(issue)/page/year: 3,22,1973

                    *** OCCUPATIONAL EXPOSURE LIMITS ***
 
   OEL-AUSTRALIA:TWA 0.05 mg(Hg)/m3;Skin JAN 1993
   
   OEL-BELGIUM:TWA 0.05 mg(Hg)/m3;Skin JAN 1993
   
   OEL-DENMARK:TWA 0.05 mg(Hg)/m3 JAN 1993
   
   OEL-FINLAND:TWA 0.05 mg(Hg)/m3 JAN 1993
   
   OEL-FRANCE:TWA 0.05 mg(Hg)/m3 JAN 1993
   
   OEL-GERMANY:TWA 0.01 ppm (0.1 mg(Hg)/m3) JAN 1993
   
   OEL-HUNGARY:TWA 0.02 mg(Hg)/m3;STEL 0.04 mg(Hg)/m3 JAN 1993
   
   OEL-JAPAN:TWA 0.05 mg(Hg)/m3 JAN 1993
   
   OEL-THE NETHERLANDS:TWA 0.05 mg(Hg)/m3;STEL 0.15 mg(Hg)/m3  JAN 1993
   
   OEL-THE PHILIPPINES:TWA 0.05 mg(Hg)/m3 JAN 1993
   
   OEL-POLAND:TWA 0.01 mg(Hg)/m3 JAN 1993
   
   OEL-RUSSIA:TWA 0.05 mg(Hg)/m3;STEL 0.01 mg(Hg)/m3 JAN 1993
   
   OEL-SWEDEN:TWA 0.05 mg(Hg)/m3 JAN 1993
   
   OEL-THAILAND:STEL 0.05 mg(Hg)/m3 JAN 1993
   
   OEL-UNITED KINGDOM:TWA 0.05 mg(Hg)/m3;STEL 0.15 mg(Hg)/m3  JAN 1993
   
   OEL IN BULGARIA, COLOMBIA, JORDAN, KOREA check ACGIH TLV
   
   OEL IN NEW ZEALAND, SINGAPORE, VIETNAM check ACGIH TLV

         *** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA ***

NIOSH RECOMMENDED EXPOSURE LEVEL (REL) :
   NIOSH REL TO MERCURY, ORGANO-air:TWA 0.01 mg/m3;STEL 0.03 mg/m3 (Sk)
REFERENCE :
   NIOSH* National Institute for Occupational Safety and Health, U.S. Dept. of
   Health, Education, and Welfare, Reports and Memoranda.
   Volume(issue)/page/year: DHHS #92-100,1992

 
                            *** END OF RECORD ***