*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : PB0393000
CHEMICAL NAME           : Methanesulfonamide,
                          N-(4-(9-acridinylamino)-3-methoxyphenyl)-,
                          mono(2-hydroxyethanesulfonate)
CAS REGISTRY NUMBER     : 80277-14-1
LAST UPDATED            : 199410
DATA ITEMS CITED        : 3
MOLECULAR FORMULA       : C21-H19-N3-O3-S.C2-H2-O4-S
MOLECULAR WEIGHT        : 515.59
COMPOUND DESCRIPTOR     : Mutagen
SYNONYMS/TRADE NAMES :
   * 4'-(9-Acridinylamino)methanesulfon-m-anisidide compd. with  
   2-hydroxyethanesulfonic acid
   * N-(4-(9-Acridinylamino)-3-methoxyphenyl)methanesulfonamide  
   mono(2-hydroxyethanesulfonate)
   * Isothionate salt of amsacrine
   * Methanesulfon-m-anisidide, 4'-(9-acridinylamino)-, compd. with  
   2-hydroxyethanesulfonic acid
 
                       *** HEALTH HAZARD DATA ***
 
                            ** MUTATION DATA **
 
TYPE OF TEST            : Micronucleus test
TEST SYSTEM             : Rodent - mouse Embryo
DOSE/DURATION           : 40 ug/L
REFERENCE :
   MUREAV Mutation Research.  (Elsevier Science Pub. B.V., POB 211, 1000 AE
   Amsterdam, Netherlands) V.1-    1964-  Volume(issue)/page/year: 170,133,1986
 
TYPE OF TEST            : Morphological transformation
TEST SYSTEM             : Rodent - mouse Embryo
DOSE/DURATION           : 20 ug/L
REFERENCE :
   MUREAV Mutation Research.  (Elsevier Science Pub. B.V., POB 211, 1000 AE
   Amsterdam, Netherlands) V.1-    1964-  Volume(issue)/page/year: 170,133,1986
 
TYPE OF TEST            : Cytogenetic analysis
TEST SYSTEM             : Rodent - mouse Embryo
DOSE/DURATION           : 10 ug/L
REFERENCE :
   MUREAV Mutation Research.  (Elsevier Science Pub. B.V., POB 211, 1000 AE
   Amsterdam, Netherlands) V.1-    1964-  Volume(issue)/page/year: 170,133,1986
 
                            *** END OF RECORD ***