*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : PB0395000
CHEMICAL NAME           : Methanesulfonamide,
                          N-(4-(9-acridinylamino)-3-methoxyphenyl)-,
                          monomethanesulfonate
CAS REGISTRY NUMBER     : 54301-16-5
LAST UPDATED            : 199410
DATA ITEMS CITED        : 3
MOLECULAR FORMULA       : C21-H19-N3-O3-S.C-H4-O3-S
MOLECULAR WEIGHT        : 489.60
WISWESSER LINE NOTATION : T C666 BNJ IMR BO1 DMSW1 &WSQ1
COMPOUND DESCRIPTOR     : Drug
                          Mutagen
SYNONYMS/TRADE NAMES :
   * 4'-(9-Acridinylamino)-3'-methoxymethanesulfonanilide methanesulfonate
   * N-(4-(9-Acridinylamino)-3-methoxyphenyl)methanesulfonamide  
   methanesulfonate
   * CI-880 methylsulfonate
   * Methanesulfonanilide, 4'-(9-acridinylamino)-3'-methoxy-, methanesulfonate
   * NSC 154948
   * SN 11841
 
                       *** HEALTH HAZARD DATA ***
 
                        ** ACUTE TOXICITY DATA **
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 185 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   NCISP* National Cancer Institute Screening Program Data Summary,
   Developmental Therapeutics Program. (Bethesda, MD 20205)
   Volume(issue)/page/year: JAN1986
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intraperitoneal
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 24 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   ANYAA9 Annals of the New York Academy of Sciences.  (New York Academy of
   Sciences, 2 E. 63rd St., New York, NY 10021)  V.1-    1877-
   Volume(issue)/page/year: 284,463,1977
 
                            ** MUTATION DATA **
 
TYPE OF TEST            : Mutation in microorganisms
TEST SYSTEM             : Bacteria - Salmonella typhimurium
DOSE/DURATION           : 249 umol/L
REFERENCE :
   JMCMAR Journal of Medicinal Chemistry.  (American Chemical Soc.,
   Distribution Office Dept. 223, POB POB 57136, West End Stn., Washington, DC
   20037)  V.6-    1963-  Volume(issue)/page/year: 22,251,1979
 
                            *** END OF RECORD ***