*** CHEMICAL IDENTIFICATION *** RTECS NUMBER : PB0395000 CHEMICAL NAME : Methanesulfonamide, N-(4-(9-acridinylamino)-3-methoxyphenyl)-, monomethanesulfonate CAS REGISTRY NUMBER : 54301-16-5 LAST UPDATED : 199410 DATA ITEMS CITED : 3 MOLECULAR FORMULA : C21-H19-N3-O3-S.C-H4-O3-S MOLECULAR WEIGHT : 489.60 WISWESSER LINE NOTATION : T C666 BNJ IMR BO1 DMSW1 &WSQ1 COMPOUND DESCRIPTOR : Drug Mutagen SYNONYMS/TRADE NAMES : * 4'-(9-Acridinylamino)-3'-methoxymethanesulfonanilide methanesulfonate * N-(4-(9-Acridinylamino)-3-methoxyphenyl)methanesulfonamide methanesulfonate * CI-880 methylsulfonate * Methanesulfonanilide, 4'-(9-acridinylamino)-3'-methoxy-, methanesulfonate * NSC 154948 * SN 11841 *** HEALTH HAZARD DATA *** ** ACUTE TOXICITY DATA ** TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Oral SPECIES OBSERVED : Rodent - mouse DOSE/DURATION : 185 mg/kg TOXIC EFFECTS : Details of toxic effects not reported other than lethal dose value REFERENCE : NCISP* National Cancer Institute Screening Program Data Summary, Developmental Therapeutics Program. (Bethesda, MD 20205) Volume(issue)/page/year: JAN1986 TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Intraperitoneal SPECIES OBSERVED : Rodent - mouse DOSE/DURATION : 24 mg/kg TOXIC EFFECTS : Details of toxic effects not reported other than lethal dose value REFERENCE : ANYAA9 Annals of the New York Academy of Sciences. (New York Academy of Sciences, 2 E. 63rd St., New York, NY 10021) V.1- 1877- Volume(issue)/page/year: 284,463,1977 ** MUTATION DATA ** TYPE OF TEST : Mutation in microorganisms TEST SYSTEM : Bacteria - Salmonella typhimurium DOSE/DURATION : 249 umol/L REFERENCE : JMCMAR Journal of Medicinal Chemistry. (American Chemical Soc., Distribution Office Dept. 223, POB POB 57136, West End Stn., Washington, DC 20037) V.6- 1963- Volume(issue)/page/year: 22,251,1979 *** END OF RECORD ***