*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : PB0475320
CHEMICAL NAME           : Methanesulfonamide,
                          N-(5-(2-((1,1-dimethyl-2-phenylethyl)amino)-1-hydroxy
                          ethyl)-2- hydroxyphenyl)-, monohydrochloride, (+-)-
CAS REGISTRY NUMBER     : 79561-61-8
LAST UPDATED            : 199401
DATA ITEMS CITED        : 2
MOLECULAR FORMULA       : C19-H26-N2-O4-S.Cl-H
MOLECULAR WEIGHT        : 414.99
COMPOUND DESCRIPTOR     : Tumorigen
SYNONYMS/TRADE NAMES :
   * (+-)-Zinterol hydrochloride
 
                       *** HEALTH HAZARD DATA ***
 
                          ** TUMORIGENIC DATA **
 
TYPE OF TEST            : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : 2920 mg/kg/2Y-C
TOXIC EFFECTS :
   Tumorigenic - equivocal tumorigenic agent by RTECS criteria
   Reproductive - Tumorigenic effects - ovarian tumors
   Tumorigenic - tumor types after systemic administration not seen
   spontaneously
REFERENCE :
   JACTDZ Journal of the American College of Toxicology.  (Mary Ann Liebert,
   Inc., 1651 Third Ave., New York, NY 10128)  V.1-12, 1982-1993. Discontinued.
    Volume(issue)/page/year: 12,13,1993
 
TYPE OF TEST            : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : 36500 mg/kg/1Y-C
TOXIC EFFECTS :
   Tumorigenic - equivocal tumorigenic agent by RTECS criteria
   Reproductive - Tumorigenic effects - ovarian tumors
   Tumorigenic - tumor types after systemic administration not seen
   spontaneously
REFERENCE :
   JACTDZ Journal of the American College of Toxicology.  (Mary Ann Liebert,
   Inc., 1651 Third Ave., New York, NY 10128)  V.1-12, 1982-1993. Discontinued.
    Volume(issue)/page/year: 12,13,1993
 
                            *** END OF RECORD ***