*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : PB8938000
CHEMICAL NAME           : 2,6-Methano-3-benzazocin-8-ol,
                          1,2,3,4,5,6-hexahydro-3,11-dimethyl-6-phenyl-,
                          hydrochloride, (-)-
CAS REGISTRY NUMBER     : 21141-28-6
LAST UPDATED            : 199107
DATA ITEMS CITED        : 2
MOLECULAR FORMULA       : C20-H23-N-O.Cl-H
MOLECULAR WEIGHT        : 329.90
COMPOUND DESCRIPTOR     : Drug
SYNONYMS/TRADE NAMES :
   * GPA 1657
   *   l-1,2,3,4,5,6-Hexahydro-3,11-beta-dimethyl-6-phenyl-2,6-methano-3-benzac
     ocin-8-ol HCl
 
                       *** HEALTH HAZARD DATA ***
 
                        ** ACUTE TOXICITY DATA **
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 185 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   JMCMAR Journal of Medicinal Chemistry.  (American Chemical Soc.,
   Distribution Office Dept. 223, POB POB 57136, West End Stn., Washington, DC
   20037)  V.6-    1963-  Volume(issue)/page/year: 13,488,1970
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intraperitoneal
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 68 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   JMCMAR Journal of Medicinal Chemistry.  (American Chemical Soc.,
   Distribution Office Dept. 223, POB POB 57136, West End Stn., Washington, DC
   20037)  V.6-    1963-  Volume(issue)/page/year: 13,488,1970
 
                            *** END OF RECORD ***