*** CHEMICAL IDENTIFICATION ***
RTECS NUMBER : PB9223000
CHEMICAL NAME : 7,9a-alpha-Methano-9aH-cyclopenta(b)heptalene-4,8,10,
11,11a-beta,(1H)-pent ol, 2-beta,3-beta-
epoxy-2,3,3a-beta,4,4a-beta,5,6,7-beta,8,9,10-beta,11
-alpha-dodecahydro-1, 1,4-beta,8-beta- tetramethyl-
CAS REGISTRY NUMBER : 28894-74-8
OTHER CAS REGISTRY NOS. : 28836-75-1
LAST UPDATED : 199806
DATA ITEMS CITED : 3
MOLECULAR FORMULA : C20-H32-O6
MOLECULAR WEIGHT : 368.52
WISWESSER LINE NOTATION : T G3 E5 B765 A 1B Q BX HOTJ CQ DQ EQ F1 F1 KQ K1 PQ
P1
SYNONYMS/TRADE NAMES :
* Deacetyllyoniatoxin
* Grayanotoxane-5,6,7,10,16-pentol, 2,3-epoxy-,
(2-beta,3-beta,6-beta,7-alpha)-
* Lyoniol B
*** HEALTH HAZARD DATA ***
** ACUTE TOXICITY DATA **
TYPE OF TEST : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE : Intraperitoneal
SPECIES OBSERVED : Rodent - mouse
DOSE/DURATION : 800 ug/kg
TOXIC EFFECTS :
Cardiac - arrhythmias (including changes in conduction)
Lungs, Thorax, or Respiration - respiratory depression
REFERENCE :
CPBTAL Chemical and Pharmaceutical Bulletin. (Japan Pub. Trading Co., USA,
1255 Howard St., San Francisco, CA 94103) V.6- 1958-
Volume(issue)/page/year: 22,884,1974
TYPE OF TEST : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE : Unreported
SPECIES OBSERVED : Rodent - mouse
DOSE/DURATION : 1100 ug/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
CPBTAL Chemical and Pharmaceutical Bulletin. (Japan Pub. Trading Co., USA,
1255 Howard St., San Francisco, CA 94103) V.6- 1958-
Volume(issue)/page/year: 9,171,1961
TYPE OF TEST : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE : Intravenous
SPECIES OBSERVED : Rodent - guinea pig
DOSE/DURATION : 90 ug/kg
TOXIC EFFECTS :
Behavioral - convulsions or effect on seizure threshold
Lungs, Thorax, or Respiration - other changes
REFERENCE :
ARTODN Archives of Toxicology. (Springer-Verlag, Heidelberger Pl. 3, D-1000
Berlin 33, Fed. Rep. Ger.) V.32- 1974- Volume(issue)/page/year:
44,259,1980
*** END OF RECORD ***