*** CHEMICAL IDENTIFICATION ***
RTECS NUMBER : PB9230000
CHEMICAL NAME : 7,9a-Methano-9aH-cyclopenta(b)heptalene-4,8,10,11,11a
(1H)-pentol, 2,3-epoxydodecahydro-1,1,
4,8-tetramethyl-, 11-acetate,
(2R,3S,3as,4R,4ar,7R,8R,9ar,10S,11R,11aR)-
CAS REGISTRY NUMBER : 31136-61-5
BEILSTEIN REFERENCE NO. : 5637282
LAST UPDATED : 199806
DATA ITEMS CITED : 3
MOLECULAR FORMULA : C22-H34-O7
MOLECULAR WEIGHT : 410.56
WISWESSER LINE NOTATION : T G3 E5 B765 A 1B Q BX HOTJ CQ DQ EOV1 F1 F1 KQ K1 PQ
P1
SYNONYMS/TRADE NAMES :
* Grayanotoxane-5,6,7,10,16-pentol, 2,3-epoxy-, 6-acetate,
(2-beta,3-beta,6-beta,7-alpha)-
* Lyoniatoxin
* Lyoniol A
*** HEALTH HAZARD DATA ***
** ACUTE TOXICITY DATA **
TYPE OF TEST : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE : Intraperitoneal
SPECIES OBSERVED : Rodent - mouse
DOSE/DURATION : 3010 ug/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
TXAPA9 Toxicology and Applied Pharmacology. (Academic Press, Inc., 1 E.
First St., Duluth, MN 55802) V.1- 1959- Volume(issue)/page/year:
35,303,1976
TYPE OF TEST : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE : Unreported
SPECIES OBSERVED : Rodent - mouse
DOSE/DURATION : 4900 ug/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
CPBTAL Chemical and Pharmaceutical Bulletin. (Japan Pub. Trading Co., USA,
1255 Howard St., San Francisco, CA 94103) V.6- 1958-
Volume(issue)/page/year: 9,171,1961
TYPE OF TEST : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE : Intravenous
SPECIES OBSERVED : Rodent - guinea pig
DOSE/DURATION : 400 ug/kg
TOXIC EFFECTS :
Behavioral - convulsions or effect on seizure threshold
Lungs, Thorax, or Respiration - other changes
REFERENCE :
ARTODN Archives of Toxicology. (Springer-Verlag, Heidelberger Pl. 3, D-1000
Berlin 33, Fed. Rep. Ger.) V.32- 1974- Volume(issue)/page/year:
44,259,1980
*** END OF RECORD ***