*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : PB9266500
CHEMICAL NAME           : 7,14-Methano-2H,6H-dipyrido(1,2-a:1',2'-e)(1,5)diazoc
                          in-6-one, dodecahydro-, monohydrochloride,
                          (7R-(7-alpha,7a-alpha,14-alpha,14a-beta))-
CAS REGISTRY NUMBER     : 40136-09-2
LAST UPDATED            : 198706
DATA ITEMS CITED        : 2
MOLECULAR FORMULA       : C15-H24-N2-O.Cl-H
MOLECULAR WEIGHT        : 284.87
SYNONYMS/TRADE NAMES :
   * 17-Oxosparteine hydrochloride
   * Oxysparteine hydrochloride
 
                       *** HEALTH HAZARD DATA ***
 
                        ** ACUTE TOXICITY DATA **
 
TYPE OF TEST            : LDLo - Lowest published lethal dose
ROUTE OF EXPOSURE       : Subcutaneous
SPECIES OBSERVED        : Rodent - rabbit
DOSE/DURATION           : 600 mg/kg
TOXIC EFFECTS :
   Behavioral - tremor
   Cardiac - pulse rate
   Lungs, Thorax, or Respiration - respiratory stimulation
REFERENCE :
   JPETAB Journal of Pharmacology and Experimental Therapeutics.  (Williams &
   Wilkins Co., 428 E. Preston St., Baltimore, MD 21202)  V.1-    1909/10-
   Volume(issue)/page/year: 27,431,1926
 
TYPE OF TEST            : LDLo - Lowest published lethal dose
ROUTE OF EXPOSURE       : Parenteral
SPECIES OBSERVED        : Amphibian - frog
DOSE/DURATION           : 2 gm/kg
TOXIC EFFECTS :
   Sense Organs and Special Senses (Eye) - mydriasis (pupillary dilation)
   Behavioral - ataxia
   Cardiac - pulse rate
REFERENCE :
   JPETAB Journal of Pharmacology and Experimental Therapeutics.  (Williams &
   Wilkins Co., 428 E. Preston St., Baltimore, MD 21202)  V.1-    1909/10-
   Volume(issue)/page/year: 27,431,1926
 
                            *** END OF RECORD ***