*** CHEMICAL IDENTIFICATION *** RTECS NUMBER : PB9268200 CHEMICAL NAME : 1,5-Methano-1H,3H,11H-furo(3,4-g)pyrano(3,2-b)xanthen e-1-crotonic acid, 3a,4,5,7-tetrahydro- 8-hydroxy-alpha,3,3,11-tetramethyl-13-(3-methyl-2-but enyl)-11-(4-methyl-3- pentenyl)-7,15- dioxo-, (Z)- CAS REGISTRY NUMBER : 2752-65-0 LAST UPDATED : 199503 DATA ITEMS CITED : 4 MOLECULAR FORMULA : C38-H44-O8 MOLECULAR WEIGHT : 628.82 COMPOUND DESCRIPTOR : Drug Natural Product SYNONYMS/TRADE NAMES : * Cambogic acid * beta-Guttiferin * B''-Guttiferin *** HEALTH HAZARD DATA *** ** ACUTE TOXICITY DATA ** TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Intraperitoneal SPECIES OBSERVED : Rodent - rat DOSE/DURATION : 88 mg/kg TOXIC EFFECTS : Liver - other changes REFERENCE : IJEBA6 Indian Journal of Experimental Biology. (Publications & Information Directorate, CSIR, Hillside Rd., New Delhi 110 012, India) V.1- 1963- Volume(issue)/page/year: 5,96,1967 TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Intravenous SPECIES OBSERVED : Rodent - rat DOSE/DURATION : 107 mg/kg TOXIC EFFECTS : Liver - other changes REFERENCE : IJEBA6 Indian Journal of Experimental Biology. (Publications & Information Directorate, CSIR, Hillside Rd., New Delhi 110 012, India) V.1- 1963- Volume(issue)/page/year: 5,96,1967 TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Subcutaneous SPECIES OBSERVED : Rodent - mouse DOSE/DURATION : 354 mg/kg TOXIC EFFECTS : Details of toxic effects not reported other than lethal dose value REFERENCE : 85GDA2 "CRC Handbook of Antibiotic Compounds," Vols.1- , Berdy, J., Boca Raton, FL, CRC Press, 1980- Volume(issue)/page/year: 8(1),331,1982 TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Unreported SPECIES OBSERVED : Mammal - species unspecified DOSE/DURATION : 55 mg/kg TOXIC EFFECTS : Details of toxic effects not reported other than lethal dose value REFERENCE : 85PEAG "Zhongliu Yanjiu" Cancer Review, Yu, R., et al., eds., Shanghai Science/Technology Publisher, Peop. Rep. China, 1994 Volume(issue)/page/year: -,220,1994 *** END OF RECORD ***