*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : PB9625200
CHEMICAL NAME           : 4,7-Methanoindan,
                          3a,4,5,6,7,7a-hexahydro-1,2:5,6-diepoxy-
CAS REGISTRY NUMBER     : 81-21-0
OTHER CAS REGISTRY NOS. : 106342-07-8
                          21090-47-1
                          4168-48-3
                          29475-56-7
LAST UPDATED            : 199801
DATA ITEMS CITED        : 9
MOLECULAR FORMULA       : C10-H12-O2
MOLECULAR WEIGHT        : 164.22
WISWESSER LINE NOTATION : T D3 C55 J35 A ED KOTJ
COMPOUND DESCRIPTOR     : Primary Irritant
SYNONYMS/TRADE NAMES :
   * Bicyclopentadiene dioxide
   * 1,2:5,6-Diepoxyhexahydro-4,7-methanoindan
   * 1,2:5,6-Diepoxy-3a,4,5,6,7,7a-hexahydro-4,7-methanoindan
   * Dicyclopentadiene diepoxide
   * Dicyclopentadiene dioxide
   * EP 207
   * Epoxide 207
   * 2,4-Methano-2H-bisoxireno(a,f)indene, octahydro-
   * 4,7-Methanoindan, 1,2:5,6-diepoxyhexahydro-
   * 4,7-Methanoindan, 1,2:5,6-diepoxy-3a,4,5,6,7,7a-hexahydro-
   * 2,4-Methano-2H-indeno(1,2-b:5,6-b')bisoxirene, octahydro-
   * Unox 207
   * Unox epoxide 207
   * Unox 207X
 
                       *** HEALTH HAZARD DATA ***
 
                      ** SKIN/EYE IRRITATION DATA **
 
TYPE OF TEST            : Open irritation test
ROUTE OF EXPOSURE       : Administration onto the skin
SPECIES OBSERVED        : Rodent - rabbit
DOSE/DURATION           : 500 mg
REACTION SEVERITY       : Mild
REFERENCE :
   UCDS** Union Carbide Data Sheet.  (Union Carbide Corp., 39 Old Ridgebury
   Rd., Danbury, CT 06817)  Volume(issue)/page/year: 10/5/1961
 
                        ** ACUTE TOXICITY DATA **
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : 210 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   UCDS** Union Carbide Data Sheet.  (Union Carbide Corp., 39 Old Ridgebury
   Rd., Danbury, CT 06817)  Volume(issue)/page/year: 10/5/1961
 
TYPE OF TEST            : LDLo - Lowest published lethal dose
ROUTE OF EXPOSURE       : Intraperitoneal
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : 11 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   85JCAE "Prehled Prumyslove Toxikologie; Organicke Latky," Marhold, J.,
   Prague, Czechoslovakia, Avicenum, 1986  Volume(issue)/page/year: -,778,1986
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intravenous
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 56 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   CSLNX* U.S. Army Armament Research & Development Command, Chemical Systems
   Laboratory, NIOSH Exchange Chemicals.  (Aberdeen Proving Ground, MD 21010)
   Volume(issue)/page/year: NX#04159
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Administration onto the skin
SPECIES OBSERVED        : Rodent - rabbit
DOSE/DURATION           : 8 gm/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   UCDS** Union Carbide Data Sheet.  (Union Carbide Corp., 39 Old Ridgebury
   Rd., Danbury, CT 06817)  Volume(issue)/page/year: 10/5/1961
 
TYPE OF TEST            : LC50 - Lethal concentration, 50 percent kill
ROUTE OF EXPOSURE       : Inhalation
SPECIES OBSERVED        : Mammal - species unspecified
DOSE/DURATION           : 10 gm/m3/1H
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   85JCAE "Prehled Prumyslove Toxikologie; Organicke Latky," Marhold, J.,
   Prague, Czechoslovakia, Avicenum, 1986  Volume(issue)/page/year: -,778,1986
 
                 ** OTHER MULTIPLE DOSE TOXICITY DATA **
 
TYPE OF TEST            : TCLo - Lowest published toxic concentration
ROUTE OF EXPOSURE       : Inhalation
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : 1100 ug/m3/17W-I
TOXIC EFFECTS :
   Brain and Coverings - recordings from specific areas of CNS
   Kidney, Ureter, Bladder - proteinuria
   Kidney, Ureter, Bladder - other changes in urine composition
REFERENCE :
   TPKVAL Toksikologiya Novykh Promyshlennykh Khimicheskikh Veshchestv.
   Toxicology of New Industrial Chemical Substances.  For English translation,
   see TNICS*.  (Izdatel'stvo Meditsina, Moscow, USSR)  No.1-    1961-
   Volume(issue)/page/year: 14,131,1975

                          *** STATUS IN U.S. ***
 
   EPA TSCA Section 8(b) CHEMICAL INVENTORY
   
   EPA TSCA 8(a) PRELIMINARY ASSESSMENT INFORMATION, FINAL RULE
   FEREAC Federal Register.  (U.S. Government Printing Office, Supt. of
   Documents, Washington, DC 20402) V.1-    1936-  Volume(issue)/page/year:
   47,26992,82

 
                            *** END OF RECORD ***