*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : PC1362200
CHEMICAL NAME           : 4,7-Methano-1H-isoindole-1,3(2H)-dione,
                          3a,4,7,7a-tetrahydro-, (3a-alpha,4-beta,7-beta,7a-
                          alpha)-
CAS REGISTRY NUMBER     : 6319-06-8
LAST UPDATED            : 199406
DATA ITEMS CITED        : 3
MOLECULAR FORMULA       : C9-H9-N-O2
MOLECULAR WEIGHT        : 163.19
COMPOUND DESCRIPTOR     : Drug
SYNONYMS/TRADE NAMES :
   * Bicyclo(2.2.1)hept-5-ene-2,3-exo-cis-dicarboximide
   * K-2154
   * 5-Norbornene-2,3-dicarboximide, exo-
   * cis-exo-5-Norbornene-2,3-dicarboximide
   * Noreximida
   * Noreximide
 
                       *** HEALTH HAZARD DATA ***
 
                        ** ACUTE TOXICITY DATA **
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 562 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   DRFUD4 Drugs of the Future.  (J.R. Prous, S.A., Apartado de Correos 540,
   08080 Barcelona, Spain) V.1-    1975/76-  Volume(issue)/page/year:
   8,593,1983
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intraperitoneal
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 250 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   DRFUD4 Drugs of the Future.  (J.R. Prous, S.A., Apartado de Correos 540,
   08080 Barcelona, Spain) V.1-    1975/76-  Volume(issue)/page/year:
   8,593,1983
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intravenous
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 105 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   DRFUD4 Drugs of the Future.  (J.R. Prous, S.A., Apartado de Correos 540,
   08080 Barcelona, Spain) V.1-    1975/76-  Volume(issue)/page/year:
   8,593,1983
 
                            *** END OF RECORD ***