*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : QA5930000
CHEMICAL NAME           : Monensin,
                          21,25-deepoxy-16-deethyl-12-demethyl-26-deoxy-21,24-e
                          poxy-21-hydroxy-8,16- dimethyl- 7-O-methyl-,
                          monosodium salt, (8R)-
CAS REGISTRY NUMBER     : 129388-64-3
LAST UPDATED            : 199206
DATA ITEMS CITED        : 2
MOLECULAR FORMULA       : C37-H62-O11.Na
MOLECULAR WEIGHT        : 705.98
COMPOUND DESCRIPTOR     : Drug
SYNONYMS/TRADE NAMES :
   * Kijimicin sodium salt
 
                       *** HEALTH HAZARD DATA ***
 
                        ** ACUTE TOXICITY DATA **
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 180 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   JANTAJ Journal of Antibiotics.  (Japan Antibiotics Research Assoc., 2-20-8
   Kamiosaki, Shinagawa-ku, Tokyo, 141, Japan)  V.2-5, 1948-52;  V.21- 1968-
   Volume(issue)/page/year: 43,441,1990
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intraperitoneal
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 56 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   JANTAJ Journal of Antibiotics.  (Japan Antibiotics Research Assoc., 2-20-8
   Kamiosaki, Shinagawa-ku, Tokyo, 141, Japan)  V.2-5, 1948-52;  V.21- 1968-
   Volume(issue)/page/year: 43,441,1990
 
                            *** END OF RECORD ***