*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : QC6475000
CHEMICAL NAME           : Morphanthridine,
                          5-(3-(dimethylamino)propyl)-5,6-dihydro-,
                          monohydrochloride
CAS REGISTRY NUMBER     : 966-90-5
LAST UPDATED            : 199203
DATA ITEMS CITED        : 2
MOLECULAR FORMULA       : C19-H24-N2.Cl-H
MOLECULAR WEIGHT        : 316.91
WISWESSER LINE NOTATION : T C676 IM&T&J B3N1&1 &GH
COMPOUND DESCRIPTOR     : Drug
SYNONYMS/TRADE NAMES :
   * 5-(3-(Dimethylamino)propyl)-5,6-dihydromorphanthridine hydrochloride
   * Propazepine hydrochloride
   * Propazepin, monohydrochloride
 
                       *** HEALTH HAZARD DATA ***
 
                        ** ACUTE TOXICITY DATA **
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 350 mg/kg
TOXIC EFFECTS :
   Behavioral - convulsions or effect on seizure threshold
REFERENCE :
   AIPTAK Archives Internationales de Pharmacodynamie et de Therapie. (Heymans
   Institute of Pharmacology, De Pintelaan 185, B-9000 Ghent, Belgium)  V.4-   
   1898-  Volume(issue)/page/year: 144,481,1963
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intravenous
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 37 mg/kg
TOXIC EFFECTS :
   Behavioral - somnolence (general depressed activity)
   Behavioral - tremor
   Behavioral - convulsions or effect on seizure threshold
REFERENCE :
   AIPTAK Archives Internationales de Pharmacodynamie et de Therapie. (Heymans
   Institute of Pharmacology, De Pintelaan 185, B-9000 Ghent, Belgium)  V.4-   
   1898-  Volume(issue)/page/year: 144,481,1963
 
                            *** END OF RECORD ***