*** CHEMICAL IDENTIFICATION *** RTECS NUMBER : QC6475000 CHEMICAL NAME : Morphanthridine, 5-(3-(dimethylamino)propyl)-5,6-dihydro-, monohydrochloride CAS REGISTRY NUMBER : 966-90-5 LAST UPDATED : 199203 DATA ITEMS CITED : 2 MOLECULAR FORMULA : C19-H24-N2.Cl-H MOLECULAR WEIGHT : 316.91 WISWESSER LINE NOTATION : T C676 IM&T&J B3N1&1 &GH COMPOUND DESCRIPTOR : Drug SYNONYMS/TRADE NAMES : * 5-(3-(Dimethylamino)propyl)-5,6-dihydromorphanthridine hydrochloride * Propazepine hydrochloride * Propazepin, monohydrochloride *** HEALTH HAZARD DATA *** ** ACUTE TOXICITY DATA ** TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Oral SPECIES OBSERVED : Rodent - mouse DOSE/DURATION : 350 mg/kg TOXIC EFFECTS : Behavioral - convulsions or effect on seizure threshold REFERENCE : AIPTAK Archives Internationales de Pharmacodynamie et de Therapie. (Heymans Institute of Pharmacology, De Pintelaan 185, B-9000 Ghent, Belgium) V.4- 1898- Volume(issue)/page/year: 144,481,1963 TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Intravenous SPECIES OBSERVED : Rodent - mouse DOSE/DURATION : 37 mg/kg TOXIC EFFECTS : Behavioral - somnolence (general depressed activity) Behavioral - tremor Behavioral - convulsions or effect on seizure threshold REFERENCE : AIPTAK Archives Internationales de Pharmacodynamie et de Therapie. (Heymans Institute of Pharmacology, De Pintelaan 185, B-9000 Ghent, Belgium) V.4- 1898- Volume(issue)/page/year: 144,481,1963 *** END OF RECORD ***