*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : QC7792000
CHEMICAL NAME           : Morphinan-3,14-diol,
                          6-(bis(2-chloroethyl)amino)-17-(cyclopropylmethyl)-4,
                          5-epoxy-, dihydrochloride, (5-alpha,6-beta)-
CAS REGISTRY NUMBER     : 67025-98-3
LAST UPDATED            : 199007
DATA ITEMS CITED        : 1
MOLECULAR FORMULA       : C24-H32-Cl2-N2-O3.2Cl-H
MOLECULAR WEIGHT        : 540.40
COMPOUND DESCRIPTOR     : Drug
SYNONYMS/TRADE NAMES :
   * Chlornaltrexamine dihydrochloride
 
                       *** HEALTH HAZARD DATA ***
 
                        ** ACUTE TOXICITY DATA **
 
TYPE OF TEST            : LDLo - Lowest published lethal dose
ROUTE OF EXPOSURE       : Intracerebral
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 56 mg/kg
TOXIC EFFECTS :
   Behavioral - somnolence (general depressed activity)
REFERENCE :
   JMCMAR Journal of Medicinal Chemistry.  (American Chemical Soc.,
   Distribution Office Dept. 223, POB POB 57136, West End Stn., Washington, DC
   20037)  V.6-    1963-  Volume(issue)/page/year: 22,168,1979
 
                            *** END OF RECORD ***