*** CHEMICAL IDENTIFICATION ***
RTECS NUMBER : QD0774000
CHEMICAL NAME : Morphinan-6-alpha-ol,
7,8-didehydro-3-(2-(diethylamino)ethoxy)-4,5-alpha-ep
oxy-17-methyl-
LAST UPDATED : 198306
DATA ITEMS CITED : 3
MOLECULAR FORMULA : C23-H32-N2-O3
MOLECULAR WEIGHT : 384.57
COMPOUND DESCRIPTOR : Drug
SYNONYMS/TRADE NAMES :
* 7,8-Didehydro-3-(2-(diethylamino)ethoxy)-4,5-alpha-epoxy-17-methylmorphi
nan-6-alpha-ol
* Diethylaminoethylmorphine
*** HEALTH HAZARD DATA ***
** ACUTE TOXICITY DATA **
TYPE OF TEST : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE : Intraperitoneal
SPECIES OBSERVED : Rodent - mouse
DOSE/DURATION : 40 mg/kg
TOXIC EFFECTS :
Behavioral - somnolence (general depressed activity)
Behavioral - convulsions or effect on seizure threshold
Lungs, Thorax, or Respiration - respiratory depression
REFERENCE :
APFRAD Annales Pharmaceutiques Francaises. (SPPIF, B.P.22, F-41353 Vineuil,
France) V.1- 1943- Volume(issue)/page/year: 8,261,1950
TYPE OF TEST : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE : Subcutaneous
SPECIES OBSERVED : Rodent - mouse
DOSE/DURATION : 110 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
THERAP Therapie. (Doin, Editeurs, 8, Place de l'Odeon, F-75006 Paris,
France) V.1- 1946- Volume(issue)/page/year: 7,21,1952
TYPE OF TEST : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE : Intravenous
SPECIES OBSERVED : Rodent - mouse
DOSE/DURATION : 30 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
THERAP Therapie. (Doin, Editeurs, 8, Place de l'Odeon, F-75006 Paris,
France) V.1- 1946- Volume(issue)/page/year: 7,21,1952
*** END OF RECORD ***