*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : QD0780000
CHEMICAL NAME           : Morphinan-6-alpha-ol,
                          7,8-didehydro-3-(2-(dimethylamino)ethoxy)-4,5-alpha-e
                          poxy-17-methyl-
LAST UPDATED            : 198307
DATA ITEMS CITED        : 1
MOLECULAR FORMULA       : C21-H28-N2-O3
MOLECULAR WEIGHT        : 356.51
COMPOUND DESCRIPTOR     : Drug
SYNONYMS/TRADE NAMES :
   *   7,8-Didehydro-3-(2-(dimethylamino)ethoxy)-4,5-alpha-epoxy-17-methylmorph
     inan-6-alpha-ol
   * Diethylaminomethylmorphine
 
                       *** HEALTH HAZARD DATA ***
 
                        ** ACUTE TOXICITY DATA **
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intraperitoneal
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 110 mg/kg
TOXIC EFFECTS :
   Behavioral - somnolence (general depressed activity)
   Behavioral - convulsions or effect on seizure threshold
   Lungs, Thorax, or Respiration - respiratory depression
REFERENCE :
   APFRAD Annales Pharmaceutiques Francaises.  (SPPIF, B.P.22, F-41353 Vineuil,
   France)  V.1-    1943-  Volume(issue)/page/year: 8,261,1950
 
                            *** END OF RECORD ***