*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : QD0877000
CHEMICAL NAME           : Morphinan-6-alpha-ol,
                          7,8-didehydro-4,5-alpha-epoxy-3-methoxy-
CAS REGISTRY NUMBER     : 467-15-2
LAST UPDATED            : 198612
DATA ITEMS CITED        : 2
MOLECULAR FORMULA       : C17-H19-N-O3
MOLECULAR WEIGHT        : 285.37
WISWESSER LINE NOTATION : T B6566 B5/CO 4ABBC Q BX HO PM GHT&&TTJ FQ JO1
COMPOUND DESCRIPTOR     : Drug
SYNONYMS/TRADE NAMES :
   * N-Desmethylcodeine
   * 7,8-Didehydro-4,5-alpha-epoxy-3-methoxymorphinan-6-alpha-ol
   * Morphinan-6-ol, 7,8-didehydro-4,5-epoxy-3-methoxy-, (5-alpha,6-alpha)-
   * Norcodeine
   * N-Norcodeine
   * Normorphine 3-methyl ether
 
                       *** HEALTH HAZARD DATA ***
 
                        ** ACUTE TOXICITY DATA **
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intraperitoneal
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 365 mg/kg
TOXIC EFFECTS :
   Behavioral - convulsions or effect on seizure threshold
   Lungs, Thorax, or Respiration - dyspnea
REFERENCE :
   JPETAB Journal of Pharmacology and Experimental Therapeutics.  (Williams &
   Wilkins Co., 428 E. Preston St., Baltimore, MD 21202)  V.1-    1909/10-
   Volume(issue)/page/year: 112,191,1954
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Subcutaneous
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 600 mg/kg
TOXIC EFFECTS :
   Behavioral - analgesia
   Lungs, Thorax, or Respiration - other changes
REFERENCE :
   CPBTAL Chemical and Pharmaceutical Bulletin.  (Japan Pub. Trading Co., USA,
   1255 Howard St., San Francisco, CA 94103)  V.6-    1958-
   Volume(issue)/page/year: 19,1,1971
 
                            *** END OF RECORD ***