*** CHEMICAL IDENTIFICATION *** RTECS NUMBER : QD0910000 CHEMICAL NAME : Morphinan-14-ol, 7,8-didehydro-4,5-alpha-epoxy-3-methoxy-17-methyl- LAST UPDATED : 198502 DATA ITEMS CITED : 1 MOLECULAR FORMULA : C18-H21-N-O3 MOLECULAR WEIGHT : 299.40 COMPOUND DESCRIPTOR : Drug SYNONYMS/TRADE NAMES : * 7,8-Didehydro-4,5-alpha-epoxy-3-methoxy-17-methylmorphinan-14-ol * RAM-305 *** HEALTH HAZARD DATA *** ** ACUTE TOXICITY DATA ** TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Intravenous SPECIES OBSERVED : Rodent - mouse DOSE/DURATION : 38 mg/kg TOXIC EFFECTS : Peripheral Nerve and Sensation - local anesthetic Behavioral - altered sleep time (including change in righting reflex) Lungs, Thorax, or Respiration - respiratory depression REFERENCE : YKKZAJ Yakugaku Zasshi. Journal of Pharmacy. (Nippon Yakugakkai, 2-12-15 Shibuya, Shibuya-ku, Tokyo 150, Japan) No.1- 1881- Volume(issue)/page/year: 84,268,1964 *** END OF RECORD ***