*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : QD1440000
CHEMICAL NAME           : Morphinan-6-alpha-ol,
                          7,8-didehydro-4,5-alpha-epoxy-3-methoxy-, sulfate
LAST UPDATED            : 198906
DATA ITEMS CITED        : 2
MOLECULAR FORMULA       : C17-H19-N-O3.H2-O4-S
MOLECULAR WEIGHT        : 383.45
WISWESSER LINE NOTATION : T B6566 B5/CO 4ABBC Q BX HO PM GHT&&TTJ FQ JO1 2WSQQ
COMPOUND DESCRIPTOR     : Drug
SYNONYMS/TRADE NAMES :
   * N-Desmethylcodeine sulfate
   * 7,8-Didehydro-4,5-alpha-epoxy-3-methoxymorphinan-6-alpha-ol sulfate
   * Morphinan-6-ol, 7,8-didehydro-4,5-epoxy-3-methoxy-, sulfate,  
   (5-alpha,6-alpha)-
   * Norcodeine sulfate
   * N-Norcodeine sulfate
   * Normorphine 3-methyl ether sulfate
 
                       *** HEALTH HAZARD DATA ***
 
                        ** ACUTE TOXICITY DATA **
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Subcutaneous
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 648 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   BCPCA6 Biochemical Pharmacology.  (Pergamon Press Inc., Maxwell House,
   Fairview Park, Elmsford, NY 10523)  V.1-    1958-  Volume(issue)/page/year:
   34,3143,1985
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intracerebral
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 2200 ug/kg
TOXIC EFFECTS :
   Behavioral - convulsions or effect on seizure threshold
REFERENCE :
   JPETAB Journal of Pharmacology and Experimental Therapeutics.  (Williams &
   Wilkins Co., 428 E. Preston St., Baltimore, MD 21202)  V.1-    1909/10-
   Volume(issue)/page/year: 140,155,1963
 
                            *** END OF RECORD ***