*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : QD1659000
CHEMICAL NAME           : Morphinan-14-ol, 4,5-alpha-epoxy-3-methoxy-
CAS REGISTRY NUMBER     : 55256-27-4
OTHER CAS REGISTRY NOS. : 94152-63-3
LAST UPDATED            : 198910
DATA ITEMS CITED        : 1
MOLECULAR FORMULA       : C17-H21-N-O3
MOLECULAR WEIGHT        : 287.39
COMPOUND DESCRIPTOR     : Drug
SYNONYMS/TRADE NAMES :
   * 4,5-alpha-Epoxy-3-methoxymorphinan-14-ol
   * RAM-308
 
                       *** HEALTH HAZARD DATA ***
 
                        ** ACUTE TOXICITY DATA **
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intravenous
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 87 mg/kg
TOXIC EFFECTS :
   Peripheral Nerve and Sensation - local anesthetic
   Behavioral - altered sleep time (including change in righting reflex)
   Lungs, Thorax, or Respiration - respiratory depression
REFERENCE :
   YKKZAJ Yakugaku Zasshi.  Journal of Pharmacy.  (Nippon Yakugakkai, 2-12-15
   Shibuya, Shibuya-ku, Tokyo 150, Japan)  No.1-    1881-
   Volume(issue)/page/year: 84,268,1964
 
                            *** END OF RECORD ***