*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : QD1730000
CHEMICAL NAME           : Morphinan-3-ol, 4,5-alpha-epoxy-17-methyl-
CAS REGISTRY NUMBER     : 427-00-9
LAST UPDATED            : 199009
DATA ITEMS CITED        : 2
MOLECULAR FORMULA       : C17-H21-N-O2
MOLECULAR WEIGHT        : 271.39
WISWESSER LINE NOTATION : T B6566 B6/CO 4ABBC R BX HO PN GHT&&TTJ JQ P1
COMPOUND DESCRIPTOR     : Drug
SYNONYMS/TRADE NAMES :
   * Desomorfin
   * Desomorphine
   * Dihydrodeoxymorphine
   * Dihydrodesoxymorphine-D
   * 4,5-Epoxy-3-hydroxy-N-methylmorphinan
   * Morphine, 6-deoxy-7,8-dihydro-
   * Permonid
 
                       *** HEALTH HAZARD DATA ***
 
                        ** ACUTE TOXICITY DATA **
 
TYPE OF TEST            : LDLo - Lowest published lethal dose
ROUTE OF EXPOSURE       : Subcutaneous
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 104 mg/kg
TOXIC EFFECTS :
   Behavioral - altered sleep time (including change in righting reflex)
   Behavioral - convulsions or effect on seizure threshold
REFERENCE :
   JPETAB Journal of Pharmacology and Experimental Therapeutics.  (Williams &
   Wilkins Co., 428 E. Preston St., Baltimore, MD 21202)  V.1-    1909/10-
   Volume(issue)/page/year: 55,257,1935
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intravenous
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 27 mg/kg
TOXIC EFFECTS :
   Peripheral Nerve and Sensation - local anesthetic
   Behavioral - altered sleep time (including change in righting reflex)
   Lungs, Thorax, or Respiration - respiratory depression
REFERENCE :
   YKKZAJ Yakugaku Zasshi.  Journal of Pharmacy.  (Nippon Yakugakkai, 2-12-15
   Shibuya, Shibuya-ku, Tokyo 150, Japan)  No.1-    1881-
   Volume(issue)/page/year: 84,268,1964
 
                            *** END OF RECORD ***