*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : QD1733000
CHEMICAL NAME           : Morphinan-6-alpha-ol,
                          4,5-alpha-epoxy-17-methyl-3-(2-morpholinoethoxy)-,
                          acetate, bis(hydrogentartrate)
CAS REGISTRY NUMBER     : 74051-70-0
LAST UPDATED            : 198012
DATA ITEMS CITED        : 2
MOLECULAR FORMULA       : C25-H34-N2-O5.2C4-H6-O6
MOLECULAR WEIGHT        : 742.81
COMPOUND DESCRIPTOR     : Drug
SYNONYMS/TRADE NAMES :
   * 3-Morpholylaethyl-6-acetyl-dihydromorphin (bis-hydrogentartrate)
 
                       *** HEALTH HAZARD DATA ***
 
                        ** ACUTE TOXICITY DATA **
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Subcutaneous
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 1500 mg/kg
TOXIC EFFECTS :
   Behavioral - convulsions or effect on seizure threshold
   Behavioral - excitement
REFERENCE :
   ARZNAD Arzneimittel-Forschung. Drug Research.  (Editio Cantor Verlag,
   Postfach 1255, W-7960 Aulendorf, Fed. Rep. Ger.)  V.1-    1951-
   Volume(issue)/page/year: 8,325,1958
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intravenous
SPECIES OBSERVED        : Rodent - rabbit
DOSE/DURATION           : 800 mg/kg
TOXIC EFFECTS :
   Behavioral - convulsions or effect on seizure threshold
   Behavioral - excitement
REFERENCE :
   ARZNAD Arzneimittel-Forschung. Drug Research.  (Editio Cantor Verlag,
   Postfach 1255, W-7960 Aulendorf, Fed. Rep. Ger.)  V.1-    1951-
   Volume(issue)/page/year: 8,325,1958
 
                            *** END OF RECORD ***