*** CHEMICAL IDENTIFICATION *** RTECS NUMBER : QD2097000 CHEMICAL NAME : Morphinan-4-ol, 5,6,8,14-tetradehydro-3,6-dimethoxy-17-methyl- CAS REGISTRY NUMBER : 6878-93-9 BEILSTEIN REFERENCE NO. : 0102244 REFERENCE : 2-21-00-00167 (Beilstein Handbook Reference) LAST UPDATED : 199612 DATA ITEMS CITED : 2 MOLECULAR FORMULA : C19-H23-N-O3 MOLECULAR WEIGHT : 313.43 WISWESSER LINE NOTATION : T6 G666/FQ 2AF Q FX ON CH&&TTJ DO1 HQ IO1 O1 COMPOUND DESCRIPTOR : Drug SYNONYMS/TRADE NAMES : * Dihydrothebaine PHI * phi-Dihydrothebaine * 5,6,8,14-Tetradehydro-3,6-dimethoxy-17-methylmorphinan-4-ol *** HEALTH HAZARD DATA *** ** ACUTE TOXICITY DATA ** TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Subcutaneous SPECIES OBSERVED : Rodent - rat DOSE/DURATION : 30 mg/kg TOXIC EFFECTS : Behavioral - convulsions or effect on seizure threshold Behavioral - rigidity (including catalepsy) Behavioral - analgesia REFERENCE : AIPTAK Archives Internationales de Pharmacodynamie et de Therapie. (Heymans Institute of Pharmacology, De Pintelaan 185, B-9000 Ghent, Belgium) V.4- 1898- Volume(issue)/page/year: 254,223,1981 TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Subcutaneous SPECIES OBSERVED : Rodent - mouse DOSE/DURATION : 68 mg/kg TOXIC EFFECTS : Behavioral - convulsions or effect on seizure threshold Behavioral - rigidity (including catalepsy) Behavioral - analgesia REFERENCE : AIPTAK Archives Internationales de Pharmacodynamie et de Therapie. (Heymans Institute of Pharmacology, De Pintelaan 185, B-9000 Ghent, Belgium) V.4- 1898- Volume(issue)/page/year: 254,223,1981 *** END OF RECORD ***