*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : QD2152000
CHEMICAL NAME           : Morphinan-6-one,
                          17,17'-(2-butynylene)bis(4,5-alpha-epoxy-14-hydroxy-3
                          -methoxy-, dihydrochloride
CAS REGISTRY NUMBER     : 106301-69-3
LAST UPDATED            : 198812
DATA ITEMS CITED        : 1
MOLECULAR FORMULA       : C38-H40-N2-O8.2Cl-H
MOLECULAR WEIGHT        : 725.72
COMPOUND DESCRIPTOR     : Drug
SYNONYMS/TRADE NAMES :
   * 1,4-Bis(14-hydroxydihydronorcodeinone)-2-butyne dihydrochloride
   * Norcodeinone, N,N'-2-butynylenebis(7,8-dihydro-14-hydroxy-,  
   dihydrochloride
 
                       *** HEALTH HAZARD DATA ***
 
                        ** ACUTE TOXICITY DATA **
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intravenous
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 114 mg/kg
TOXIC EFFECTS :
   Behavioral - convulsions or effect on seizure threshold
   Behavioral - ataxia
   Lungs, Thorax, or Respiration - dyspnea
REFERENCE :
   YKKZAJ Yakugaku Zasshi.  Journal of Pharmacy.  (Nippon Yakugakkai, 2-12-15
   Shibuya, Shibuya-ku, Tokyo 150, Japan)  No.1-    1881-
   Volume(issue)/page/year: 84,255,1964
 
                            *** END OF RECORD ***