*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : QD2165000
CHEMICAL NAME           : Morphinan-6-one,
                          7,8-didehydro-4,5-alpha-epoxy-14-hydroxy-3-methoxy-17
                          -methyl-, N-oxide
CAS REGISTRY NUMBER     : 19763-77-0
LAST UPDATED            : 198703
DATA ITEMS CITED        : 2
MOLECULAR FORMULA       : C18-H21-N-O5
MOLECULAR WEIGHT        : 331.40
WISWESSER LINE NOTATION : T B6566 B6/CO 4ABBC R BX FV HO PK GHT&&TTJ CQ JO1 PO
                          P1
COMPOUND DESCRIPTOR     : Drug
SYNONYMS/TRADE NAMES :
   * A/Viii
   *   7,8-Didehydro-4,5-alpha-epoxy-14-hydroxy-3-methoxy-17-methylmorphinan-6-
     one N-oxide
   * Dihydrooxycodeinon-N-oxyd
 
                       *** HEALTH HAZARD DATA ***
 
                        ** ACUTE TOXICITY DATA **
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Subcutaneous
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 980 mg/kg
TOXIC EFFECTS :
   Behavioral - convulsions or effect on seizure threshold
REFERENCE :
   ARZNAD Arzneimittel-Forschung. Drug Research.  (Editio Cantor Verlag,
   Postfach 1255, W-7960 Aulendorf, Fed. Rep. Ger.)  V.1-    1951-
   Volume(issue)/page/year: 7,594,1957
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intravenous
SPECIES OBSERVED        : Rodent - rabbit
DOSE/DURATION           : 75 mg/kg
TOXIC EFFECTS :
   Behavioral - convulsions or effect on seizure threshold
REFERENCE :
   ARZNAD Arzneimittel-Forschung. Drug Research.  (Editio Cantor Verlag,
   Postfach 1255, W-7960 Aulendorf, Fed. Rep. Ger.)  V.1-    1951-
   Volume(issue)/page/year: 7,594,1957
 
                            *** END OF RECORD ***