*** CHEMICAL IDENTIFICATION ***
RTECS NUMBER : QD2185000
CHEMICAL NAME : Morphinan-6-one,
4,5-epoxy-3,14-dihydroxy-17-(2-propynyl)-, (5-alpha)-
CAS REGISTRY NUMBER : 73232-47-0
BEILSTEIN REFERENCE NO. : 0840922
LAST UPDATED : 199612
DATA ITEMS CITED : 3
MOLECULAR FORMULA : C19-H19-N-O4
MOLECULAR WEIGHT : 325.39
COMPOUND DESCRIPTOR : Drug
SYNONYMS/TRADE NAMES :
* 7,8-Dihydro-14-hydroxy-N-(2-propynyl)normorphinone
* Normorphinone, 7,8-dihydro-14-hydroxy-N-(2-propynyl)-
* RAM-302
*** HEALTH HAZARD DATA ***
** ACUTE TOXICITY DATA **
TYPE OF TEST : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE : Oral
SPECIES OBSERVED : Rodent - mouse
DOSE/DURATION : 3 gm/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
YKKZAJ Yakugaku Zasshi. Journal of Pharmacy. (Nippon Yakugakkai, 2-12-15
Shibuya, Shibuya-ku, Tokyo 150, Japan) No.1- 1881-
Volume(issue)/page/year: 84,255,1964
TYPE OF TEST : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE : Subcutaneous
SPECIES OBSERVED : Rodent - mouse
DOSE/DURATION : >2 gm/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
YKKZAJ Yakugaku Zasshi. Journal of Pharmacy. (Nippon Yakugakkai, 2-12-15
Shibuya, Shibuya-ku, Tokyo 150, Japan) No.1- 1881-
Volume(issue)/page/year: 84,255,1964
TYPE OF TEST : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE : Intravenous
SPECIES OBSERVED : Rodent - mouse
DOSE/DURATION : 340 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
YKKZAJ Yakugaku Zasshi. Journal of Pharmacy. (Nippon Yakugakkai, 2-12-15
Shibuya, Shibuya-ku, Tokyo 150, Japan) No.1- 1881-
Volume(issue)/page/year: 84,280,1964
*** END OF RECORD ***