*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : QD2470000
CHEMICAL NAME           : Morphinan-6-one,
                          4,5-alpha-epoxy-14-hydroxy-3-methoxy-17-methyl-,
                          hydrochloride
CAS REGISTRY NUMBER     : 124-90-3
LAST UPDATED            : 199012
DATA ITEMS CITED        : 5
MOLECULAR FORMULA       : C18-H21-N-O4.Cl-H
MOLECULAR WEIGHT        : 351.86
SYNONYMS/TRADE NAMES :
   * Dihydrone hydrochloride
   * Dihydrooxycodeinone hydrochloride
   * Dihydroxycodeinone hydrochloride
   * Dinarkon
   * 4,5-Epoxy-14-hydroxy-3-methoxy-17-methyl-morphinan-6-one, hydrochloride,  
   (5-alpha)-
   * Eubine
   * Eucodal
   * Eukodal
   * Eutagen
   * 14-Hydroxydihydrocodeinone hydrochloride
   * Oxikon
   * Oxycodone hydrochloride
   * Oxycodon hydrochloride
   * Oxycon
   * Oxykodal
   * Oxykon
   * Pancodine
   * Percodan hydrochloride
   * Stupenone
   * Tecodin
   * Tecodine
   * Tekodin
   * Thecodin
   * Thecodine
   * Thekodin
 
                       *** HEALTH HAZARD DATA ***
 
                        ** ACUTE TOXICITY DATA **
 
TYPE OF TEST            : LDLo - Lowest published lethal dose
ROUTE OF EXPOSURE       : Subcutaneous
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 350 ug/kg
TOXIC EFFECTS :
   Behavioral - analgesia
   Lungs, Thorax, or Respiration - other changes
REFERENCE :
   AEPPAE Naunyn-Schmiedeberg's Archiv fuer Experimentelle Pathologie und
   Pharmakologie.  (Berlin, Ger.) V.110-253, 1925-66.  For publisher
   information, see NSAPCC.  Volume(issue)/page/year: 194,296,1940
 
TYPE OF TEST            : LDLo - Lowest published lethal dose
ROUTE OF EXPOSURE       : Intravenous
SPECIES OBSERVED        : Mammal - cat
DOSE/DURATION           : 2500 ug/kg
TOXIC EFFECTS :
   Behavioral - analgesia
   Lungs, Thorax, or Respiration - other changes
REFERENCE :
   AEPPAE Naunyn-Schmiedeberg's Archiv fuer Experimentelle Pathologie und
   Pharmakologie.  (Berlin, Ger.) V.110-253, 1925-66.  For publisher
   information, see NSAPCC.  Volume(issue)/page/year: 194,296,1940
 
TYPE OF TEST            : LDLo - Lowest published lethal dose
ROUTE OF EXPOSURE       : Subcutaneous
SPECIES OBSERVED        : Rodent - rabbit
DOSE/DURATION           : 80 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   HBAMAK "Abdernalden's Handbuch der Biologischen Arbeitsmethoden." (Leipzig,
   Ger. Dem. Rep.)  Volume(issue)/page/year: 4,1289,1935
 
TYPE OF TEST            : LDLo - Lowest published lethal dose
ROUTE OF EXPOSURE       : Intravenous
SPECIES OBSERVED        : Rodent - rabbit
DOSE/DURATION           : 45 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   HBAMAK "Abdernalden's Handbuch der Biologischen Arbeitsmethoden." (Leipzig,
   Ger. Dem. Rep.)  Volume(issue)/page/year: 4,1289,1935
 
TYPE OF TEST            : LDLo - Lowest published lethal dose
ROUTE OF EXPOSURE       : Subcutaneous
SPECIES OBSERVED        : Amphibian - frog
DOSE/DURATION           : 500 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   HBAMAK "Abdernalden's Handbuch der Biologischen Arbeitsmethoden." (Leipzig,
   Ger. Dem. Rep.)  Volume(issue)/page/year: 4,1289,1935
 
                            *** END OF RECORD ***