*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : QD2650000
CHEMICAL NAME           : Morphinan-6-one,
                          4,5-alpha-epoxy-3-hydroxy-17-methyl-, N-oxide,
                          ditartarate
CAS REGISTRY NUMBER     : 37764-28-6
LAST UPDATED            : 198703
DATA ITEMS CITED        : 2
MOLECULAR FORMULA       : C17-H19-N-O4
MOLECULAR WEIGHT        : 301.37
WISWESSER LINE NOTATION : T B6566 B6/CO 4ABBC R BX FV HO PK GHT&&TTJ PO P1
                          &QVYQYQVQ 2
COMPOUND DESCRIPTOR     : Drug
SYNONYMS/TRADE NAMES :
   * A/VI
   * Dihydromorphinon-N-oxyd-ditartarat
   * 4,5-alpha-Epoxy-3-hydroxy-17-methylmorphinan-6-one N-oxide tartarate
 
                       *** HEALTH HAZARD DATA ***
 
                        ** ACUTE TOXICITY DATA **
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Subcutaneous
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 2 gm/kg
TOXIC EFFECTS :
   Behavioral - convulsions or effect on seizure threshold
REFERENCE :
   ARZNAD Arzneimittel-Forschung. Drug Research.  (Editio Cantor Verlag,
   Postfach 1255, W-7960 Aulendorf, Fed. Rep. Ger.)  V.1-    1951-
   Volume(issue)/page/year: 7,594,1957
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intravenous
SPECIES OBSERVED        : Rodent - rabbit
DOSE/DURATION           : 160 mg/kg
TOXIC EFFECTS :
   Behavioral - convulsions or effect on seizure threshold
REFERENCE :
   ARZNAD Arzneimittel-Forschung. Drug Research.  (Editio Cantor Verlag,
   Postfach 1255, W-7960 Aulendorf, Fed. Rep. Ger.)  V.1-    1951-
   Volume(issue)/page/year: 7,594,1957
 
                            *** END OF RECORD ***