*** CHEMICAL IDENTIFICATION *** RTECS NUMBER : QE5270000 CHEMICAL NAME : Morpholine, 4-isopropyl-2-(alpha,alpha,alpha-trifluoro-m-tolyl)-, hydrochloride CAS REGISTRY NUMBER : 26629-86-7 LAST UPDATED : 199403 DATA ITEMS CITED : 4 MOLECULAR FORMULA : C14-H18-F3-N-O.Cl-H MOLECULAR WEIGHT : 309.79 COMPOUND DESCRIPTOR : Drug Human SYNONYMS/TRADE NAMES : * CERM-1766 * Conflictan * 4-Isopropyl-2-(alpha,alpha,alpha-trifluoro-m-tolyl)morpholine hydrochloride * Morpholine, 4-(1-methylethyl)-2-(3-(trifluoromethyl)phenyl)-, hydrochloride * Oxaflozane hydrochloride * 2-(3-Trifluoromethyl) phenyl 4-isopropyl tetrahydro 1,4-oxazine chlorhydrate *** HEALTH HAZARD DATA *** ** ACUTE TOXICITY DATA ** TYPE OF TEST : TDLo - Lowest published toxic dose ROUTE OF EXPOSURE : Oral SPECIES OBSERVED : Human - child DOSE/DURATION : 10 mg/kg TOXIC EFFECTS : Sense Organs and Special Senses (Eye) - mydriasis (pupillary dilation) Sense Organs and Special Senses (Eye) - increased intraocular pressure Behavioral - coma REFERENCE : JTCTDW Journal of Toxicology, Clinical Toxicology. (Marcel Dekker, 270 Madison Ave., New York, NY 10016) V.19- 1982- Volume(issue)/page/year: 30,123,1992 TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Oral SPECIES OBSERVED : Rodent - mouse DOSE/DURATION : 365 mg/kg TOXIC EFFECTS : Details of toxic effects not reported other than lethal dose value REFERENCE : USXXAM United States Patent Document. (U.S. Patent Office, Box 9, Washington, DC 20231) Volume(issue)/page/year: #3637680 TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Intravenous SPECIES OBSERVED : Rodent - mouse DOSE/DURATION : 80 mg/kg TOXIC EFFECTS : Details of toxic effects not reported other than lethal dose value REFERENCE : THERAP Therapie. (Doin, Editeurs, 8, Place de l'Odeon, F-75006 Paris, France) V.1- 1946- Volume(issue)/page/year: 29,81,1974 TYPE OF TEST : LDLo - Lowest published lethal dose ROUTE OF EXPOSURE : Intravenous SPECIES OBSERVED : Mammal - dog DOSE/DURATION : 6 mg/kg TOXIC EFFECTS : Lungs, Thorax, or Respiration - respiratory depression REFERENCE : THERAP Therapie. (Doin, Editeurs, 8, Place de l'Odeon, F-75006 Paris, France) V.1- 1946- Volume(issue)/page/year: 30,539,1975 *** END OF RECORD ***