*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : QI7610000
CHEMICAL NAME           : 2-Naphthacenecarboxamide,
                          N-((4-(amidinoamidino)-1-piperazinyl)methyl)-4-(dimet
                          hylamino)-
                          1,4,4a,5,5a,6,11,12a-octahydro-3,6,10,12,12a-pentahyd
                          roxy-6-methyl-1,11-di oxo-
CAS REGISTRY NUMBER     : 16545-11-2
LAST UPDATED            : 198407
DATA ITEMS CITED        : 2
MOLECULAR FORMULA       : C29-H38-N8-O8
MOLECULAR WEIGHT        : 626.75
WISWESSER LINE NOTATION : L E6 C666 BV FV CU GUTTT&J DQ EQ HQ IN1&1 MQ M1 RQ
                          GVM1- AT6N DNTJ DYUM&MYZUM
COMPOUND DESCRIPTOR     : Drug
                          Natural Product
SYNONYMS/TRADE NAMES :
   * Guameciclina
   * Guamecycline
   * Tetrabiguanide
   * Xanthomycin A
   * Xantomicina
 
                       *** HEALTH HAZARD DATA ***
 
                        ** ACUTE TOXICITY DATA **
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intraperitoneal
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 250 ug/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   85GDA2 "CRC Handbook of Antibiotic Compounds," Vols.1- ,  Berdy, J., Boca
   Raton, FL, CRC Press, 1980-  Volume(issue)/page/year: 2,290,1980
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intravenous
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 160 ug/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   85ERAY "Antibiotics: Origin, Nature, and Properties," Korzyoski, T., et al.,
   eds., Washington, DC, American Soc. for Microbiology, 1978
   Volume(issue)/page/year: 1,182,1978
 
                            *** END OF RECORD ***