*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : QI7640000
CHEMICAL NAME           : 2-Naphthacenecarboxamide,
                          7-chloro-4-(dimethylamino)-1,2,3,4,4a,5,5a,6,11,12a-d
                          ecahydro-
                          1,11-dioxo-N-(hydroxymethyl)-6-methyl-3,6,10,12,12a-p
                          entahydroxy-
CAS REGISTRY NUMBER     : 1181-54-0
BEILSTEIN REFERENCE NO. : 2715004
LAST UPDATED            : 199612
DATA ITEMS CITED        : 3
MOLECULAR FORMULA       : C23-H25-Cl-N2-O9
MOLECULAR WEIGHT        : 508.95
WISWESSER LINE NOTATION : L E6 C666 BV FV CUTTT&J DQ EQ GVM1Q HQ IN1&1 MQ M1 OG
                          RQ
COMPOUND DESCRIPTOR     : Drug
                          Natural Product
SYNONYMS/TRADE NAMES :
   * N'-Methylolo-chlortetracycline
 
                       *** HEALTH HAZARD DATA ***
 
                        ** ACUTE TOXICITY DATA **
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 2830 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   85ERAY "Antibiotics: Origin, Nature, and Properties," Korzyoski, T., et al.,
   eds., Washington, DC, American Soc. for Microbiology, 1978
   Volume(issue)/page/year: 1,501,1978
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intraperitoneal
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 273 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   85ERAY "Antibiotics: Origin, Nature, and Properties," Korzyoski, T., et al.,
   eds., Washington, DC, American Soc. for Microbiology, 1978
   Volume(issue)/page/year: 1,501,1978
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intravenous
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 115 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   85ERAY "Antibiotics: Origin, Nature, and Properties," Korzyoski, T., et al.,
   eds., Washington, DC, American Soc. for Microbiology, 1978
   Volume(issue)/page/year: 1,501,1978
 
                            *** END OF RECORD ***