*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : QI8575000
CHEMICAL NAME           : 2-Naphthacenecarboxamide,
                          4-(dimethylamino)-1,4,4a,5,5a,6,11,12a-octahydro-3,6,
                          10,12,12a-
                          pentahydroxy-N-((4-(2-hydroxyethyl)-1-piperazinyl)met
                          hyl)-6-methyl-1,11-di oxo-
CAS REGISTRY NUMBER     : 1110-80-1
LAST UPDATED            : 198502
DATA ITEMS CITED        : 1
MOLECULAR FORMULA       : C29-H38-N4-O9
MOLECULAR WEIGHT        : 586.71
WISWESSER LINE NOTATION : L E6 C666 BV FV CU GUTTT&J DQ EQ HQ IN1&1 MQ M1 RQ
                          GVM1- AT6N DNTJ D2Q
SYNONYMS/TRADE NAMES :
   * Ambraveine
   * Ambra-vena
   * N-(4-(beta-Hydroxyethyl)diethylenediamino-1-methyl)tetracycline
   * N-((4-(2-Hydroxyethyl)-1-piperazinyl)methyl)tetracycline
   * Mepiciclina
   * Mepicycline
   * Pipacycline
   * Sieromicin
   * Valtomicina
   * Valtomycin
 
                       *** HEALTH HAZARD DATA ***
 
                        ** ACUTE TOXICITY DATA **
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intravenous
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 188 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   GMITAB Gazzetta Medica Italiana.  (Turin, Italy)  V.95-142, 1936-83.
   Volume(issue)/page/year: 131,1,1972
 
                            *** END OF RECORD ***