*** CHEMICAL IDENTIFICATION ***
RTECS NUMBER : QI9278500
CHEMICAL NAME : 1-Naphthacenecarboxylic acid,
4-(((2''',3''-anhydro)-O-3,6-dideoxy-alpha-L-erythro-
hexopyranos-4-ulosyl-(1-4)-O-2,6-dideoxy-alpha-L-lyxo
-hexapyranosyl-(1-4)- 2,3,6-trideoxy-3-
(dimethylamino)-alpha-L-lyxo-hexopyranosyl)oxy)-1,2,3
,4,6,11-hexahydro-2,5 ,7-trihydroxy-2-
methyl-6,11-dioxo-, methyl ester,
(1R-(1-alpha,2-beta,4-beta))-
CAS REGISTRY NUMBER : 78173-91-8
LAST UPDATED : 199310
DATA ITEMS CITED : 3
MOLECULAR FORMULA : C41-H49-N-O15
MOLECULAR WEIGHT : 795.91
COMPOUND DESCRIPTOR : Mutagen
SYNONYMS/TRADE NAMES :
* Auramycin B
*** HEALTH HAZARD DATA ***
** ACUTE TOXICITY DATA **
TYPE OF TEST : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE : Intraperitoneal
SPECIES OBSERVED : Rodent - mouse
DOSE/DURATION : 100 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
EPXXDW European Patent Application. (U.S. Patent and Trademark Office,
Foreign Patents, Washington, DC 20231) Volume(issue)/page/year: #19302
** MUTATION DATA **
TYPE OF TEST : DNA inhibition
TEST SYSTEM : Rodent - mouse Leukocyte
DOSE/DURATION : 750 nmol/L
REFERENCE :
JANTAJ Journal of Antibiotics. (Japan Antibiotics Research Assoc., 2-20-8
Kamiosaki, Shinagawa-ku, Tokyo, 141, Japan) V.2-5, 1948-52; V.21- 1968-
Volume(issue)/page/year: 34,1596,1981
TYPE OF TEST : Mutation test systems - not otherwise specified
TEST SYSTEM : Rodent - mouse Leukocyte
DOSE/DURATION : 120 nmol/L
REFERENCE :
JANTAJ Journal of Antibiotics. (Japan Antibiotics Research Assoc., 2-20-8
Kamiosaki, Shinagawa-ku, Tokyo, 141, Japan) V.2-5, 1948-52; V.21- 1968-
Volume(issue)/page/year: 34,1596,1981
*** END OF RECORD ***