*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : QI9280900
CHEMICAL NAME           : 1-Naphthacenecarboxylic acid,
                          1,2,3,4,6,11-hexahydro-6,11-dioxo-2-ethyl-4-((4-O-(2,
                          6-
                          dideoxy-4-O-((2R-trans)-5,6-dihydro-6-methyl-5-oxo-2H
                          -pyran-2-yl)alpha-L-l yxo-hexopyranosyl)-
                          3-dimethylamino-2,3,6-trideoxy-alpha-L-lyxo-hexopyran
                          osyl)oxy)-2,5,7-trihy droxy-, methyl ester,
                          (1R-(1-alpha,2-beta,4-beta))-
CAS REGISTRY NUMBER     : 66789-14-8
OTHER CAS REGISTRY NOS. : 67298-12-8
LAST UPDATED            : 198910
DATA ITEMS CITED        : 3
MOLECULAR FORMULA       : C42-H51-N-O15
MOLECULAR WEIGHT        : 809.94
WISWESSER LINE NOTATION : L E6 C666 BV MVT&&&J DQ HQ H2 IVO1 RQ FO- FT6OTJ B1
                          DN1&1 CO- FT6OTJ B1 DQ CO- FT6O CVTJ B1
COMPOUND DESCRIPTOR     : Drug
                          Mutagen
SYNONYMS/TRADE NAMES :
   * Aclacinomycin Y
   * Aclacinomycin Y1
   * MA 144 Y
 
                       *** HEALTH HAZARD DATA ***
 
                        ** ACUTE TOXICITY DATA **
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intraperitoneal
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 40 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   JANTAJ Journal of Antibiotics.  (Japan Antibiotics Research Assoc., 2-20-8
   Kamiosaki, Shinagawa-ku, Tokyo, 141, Japan)  V.2-5, 1948-52;  V.21- 1968-
   Volume(issue)/page/year: 33,80-64,1980
 
                            ** MUTATION DATA **
 
TYPE OF TEST            : DNA inhibition
TEST SYSTEM             : Rodent - mouse Leukocyte
DOSE/DURATION           : 190 nmol/L
REFERENCE :
   JANTAJ Journal of Antibiotics.  (Japan Antibiotics Research Assoc., 2-20-8
   Kamiosaki, Shinagawa-ku, Tokyo, 141, Japan)  V.2-5, 1948-52;  V.21- 1968-
   Volume(issue)/page/year: 34,1596,1981
 
TYPE OF TEST            : Mutation test systems - not otherwise specified
TEST SYSTEM             : Rodent - mouse Leukocyte
DOSE/DURATION           : 12 nmol/L
REFERENCE :
   JANTAJ Journal of Antibiotics.  (Japan Antibiotics Research Assoc., 2-20-8
   Kamiosaki, Shinagawa-ku, Tokyo, 141, Japan)  V.2-5, 1948-52;  V.21- 1968-
   Volume(issue)/page/year: 34,1596,1981
 
                            *** END OF RECORD ***