*** CHEMICAL IDENTIFICATION *** RTECS NUMBER : QI9281400 CHEMICAL NAME : 1-Naphthacenecarboxylic acid, 1,2,3,4,6,11-hexahydro-6,11-dioxo-2-ethyl-2,5,7,10,12 - pentahydroxy-4-((2,3,6-trideoxy-4-O-(2,6-dideoxy-4-O- ((2R-trans)-tetrahydr o-6-methyl-5-oxo- 2H-pyran-2-yl)-alpha-L-lyxo-hexopyranosyl)-3-(dimethy lamino)-alpha-L-lyxo- hexopyranosyl) oxy)-, methyl ester, (1R-(1-alpha,2-beta,4-beta))- CAS REGISTRY NUMBER : 76264-94-3 LAST UPDATED : 199401 DATA ITEMS CITED : 3 MOLECULAR FORMULA : C42-H53-N-O17 MOLECULAR WEIGHT : 843.96 COMPOUND DESCRIPTOR : Drug Mutagen SYNONYMS/TRADE NAMES : * G-6 * 11-Hydroxycinerubin A * sigma-Isorhodomycin rdc * sigma-Isormn-A *** HEALTH HAZARD DATA *** ** ACUTE TOXICITY DATA ** TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Intravenous SPECIES OBSERVED : Rodent - mouse DOSE/DURATION : 28200 ug/kg TOXIC EFFECTS : Details of toxic effects not reported other than lethal dose value REFERENCE : EPXXDW European Patent Application. (U.S. Patent and Trademark Office, Foreign Patents, Washington, DC 20231) Volume(issue)/page/year: #22574 ** MUTATION DATA ** TYPE OF TEST : DNA inhibition TEST SYSTEM : Rodent - mouse Leukocyte DOSE/DURATION : 730 nmol/L REFERENCE : JANTAJ Journal of Antibiotics. (Japan Antibiotics Research Assoc., 2-20-8 Kamiosaki, Shinagawa-ku, Tokyo, 141, Japan) V.2-5, 1948-52; V.21- 1968- Volume(issue)/page/year: 34,1596,1981 TYPE OF TEST : Mutation test systems - not otherwise specified TEST SYSTEM : Rodent - mouse Leukocyte DOSE/DURATION : 66 nmol/L REFERENCE : JANTAJ Journal of Antibiotics. (Japan Antibiotics Research Assoc., 2-20-8 Kamiosaki, Shinagawa-ku, Tokyo, 141, Japan) V.2-5, 1948-52; V.21- 1968- Volume(issue)/page/year: 34,1596,1981 *** END OF RECORD ***