*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : QI9290600
CHEMICAL NAME           : 1-Naphthacenecarboxylic acid,
                          1,2,3,4,6,11-hexahydro-2,5,7-trihydroxy-6,11-dioxo-2-
                          (2-oxopropyl)-4-((2,3,6-trideoxy-4-O-(2,6-dideoxy-4-O
                          -((2R-trans)-tetrahyd ro-6-methyl-5-oxo-
                          2H-pyran-2-yl)-alpha-L-lyxo-hexopyranosyl)-3-(dimethy
                          lamino)-alpha-L-lyxo- hexopyranosyl) oxy)-, methyl
                          ester, (1R-(1-alpha,2-beta,4-beta))-
CAS REGISTRY NUMBER     : 78173-90-7
LAST UPDATED            : 199307
DATA ITEMS CITED        : 3
MOLECULAR FORMULA       : C43-H53-N-O16
MOLECULAR WEIGHT        : 839.97
COMPOUND DESCRIPTOR     : Drug
                          Mutagen
SYNONYMS/TRADE NAMES :
   * Sulfurmycin A
 
                       *** HEALTH HAZARD DATA ***
 
                        ** ACUTE TOXICITY DATA **
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intraperitoneal
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 100 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   EPXXDW European Patent Application. (U.S. Patent and Trademark Office,
   Foreign Patents, Washington, DC 20231)  Volume(issue)/page/year: #19302
 
                            ** MUTATION DATA **
 
TYPE OF TEST            : DNA inhibition
TEST SYSTEM             : Rodent - mouse Leukocyte
DOSE/DURATION           : 480 nmol/L
REFERENCE :
   JANTAJ Journal of Antibiotics.  (Japan Antibiotics Research Assoc., 2-20-8
   Kamiosaki, Shinagawa-ku, Tokyo, 141, Japan)  V.2-5, 1948-52;  V.21- 1968-
   Volume(issue)/page/year: 34,1596,1981
 
TYPE OF TEST            : Mutation test systems - not otherwise specified
TEST SYSTEM             : Rodent - mouse Leukocyte
DOSE/DURATION           : 43 nmol/L
REFERENCE :
   JANTAJ Journal of Antibiotics.  (Japan Antibiotics Research Assoc., 2-20-8
   Kamiosaki, Shinagawa-ku, Tokyo, 141, Japan)  V.2-5, 1948-52;  V.21- 1968-
   Volume(issue)/page/year: 34,1596,1981
 
                            *** END OF RECORD ***