*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : QI9294000
CHEMICAL NAME           : 5,12-Naphthacenedione,
                          8-acetyl-10-((3-amino-2,3,6-trideoxy-4-O-(3-hydroxy-1
                          -(2-hydroxy-1-
                          methylethoxy)butyl)-alpha-L-lyxo-hexopyranosyl)oxy)-7
                          ,8,9,10-tetrahydro-6, 8,11-trihydroxy-1- methoxy-,
                          (8S-cis)-
CAS REGISTRY NUMBER     : 64253-71-0
LAST UPDATED            : 199107
DATA ITEMS CITED        : 4
MOLECULAR FORMULA       : C34-H43-N-O13
MOLECULAR WEIGHT        : 673.78
COMPOUND DESCRIPTOR     : Drug
                          Mutagen
                          Natural Product
SYNONYMS/TRADE NAMES :
   * Baumycin A2
 
                       *** HEALTH HAZARD DATA ***
 
                        ** ACUTE TOXICITY DATA **
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intraperitoneal
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 15 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   JANTAJ Journal of Antibiotics.  (Japan Antibiotics Research Assoc., 2-20-8
   Kamiosaki, Shinagawa-ku, Tokyo, 141, Japan)  V.2-5, 1948-52;  V.21- 1968-
   Volume(issue)/page/year: 31,78-68,1978
 
                            ** MUTATION DATA **
 
TYPE OF TEST            : Phage inhibition capacity
TEST SYSTEM             : Bacteria - Escherichia coli
DOSE/DURATION           : 50 ng/plate
REFERENCE :
   CNREA8 Cancer Research. (Public Ledger Building, Suit 816, 6th & Chestnut
   Sts., Philadelphia, PA 19106)  V.1-    1941-  Volume(issue)/page/year:
   43,2819,1983
 
TYPE OF TEST            : DNA inhibition
TEST SYSTEM             : Rodent - mouse Leukocyte
DOSE/DURATION           : 1900 nmol/L
REFERENCE :
   JANTAJ Journal of Antibiotics.  (Japan Antibiotics Research Assoc., 2-20-8
   Kamiosaki, Shinagawa-ku, Tokyo, 141, Japan)  V.2-5, 1948-52;  V.21- 1968-
   Volume(issue)/page/year: 34,1596,1981
 
TYPE OF TEST            : Mutation test systems - not otherwise specified
TEST SYSTEM             : Rodent - mouse Leukocyte
DOSE/DURATION           : 710 nmol/L
REFERENCE :
   JANTAJ Journal of Antibiotics.  (Japan Antibiotics Research Assoc., 2-20-8
   Kamiosaki, Shinagawa-ku, Tokyo, 141, Japan)  V.2-5, 1948-52;  V.21- 1968-
   Volume(issue)/page/year: 34,1596,1981
 
                            *** END OF RECORD ***