*** CHEMICAL IDENTIFICATION ***
RTECS NUMBER : QI9329300
CHEMICAL NAME : 5,12-Naphthacenedione,
7,8,9,10-tetrahydro-7-((3-amino-2,3,6-trideoxy-alpha-
L-lyxo-
hexopyranosyl)oxy)-9-(hydroxyacetyl)-6,9,11-trihydrox
y-, (7S-cis)-
CAS REGISTRY NUMBER : 64314-52-9
BEILSTEIN REFERENCE NO. : 6081215
LAST UPDATED : 199612
DATA ITEMS CITED : 4
MOLECULAR FORMULA : C26-H27-N-O10
MOLECULAR WEIGHT : 513.54
WISWESSER LINE NOTATION : L E6 C666 BV MVT&&&J DQ HV1Q HQ KQ FO- FT6OTJ B1 CQ
DZ
COMPOUND DESCRIPTOR : Mutagen
SYNONYMS/TRADE NAMES :
* 4-Demethoxyadriamycin
* 4-Demethoxydoxorubicin
*** HEALTH HAZARD DATA ***
** MUTATION DATA **
TYPE OF TEST : Mutation in microorganisms
TEST SYSTEM : Bacteria - Salmonella typhimurium
DOSE/DURATION : 2 ug/plate
REFERENCE :
ENMUDM Environmental Mutagenesis. (New York, NY) V.1-9, 1979-87. For
publisher information, see EMMUEG. Volume(issue)/page/year: 7,129,1985
TYPE OF TEST : DNA damage
TEST SYSTEM : Human Cells - not otherwise specified
DOSE/DURATION : 50 ug/L
REFERENCE :
BCPCA6 Biochemical Pharmacology. (Pergamon Press Inc., Maxwell House,
Fairview Park, Elmsford, NY 10523) V.1- 1958- Volume(issue)/page/year:
38,3713,1989
TYPE OF TEST : Unscheduled DNA synthesis
TEST SYSTEM : Rodent - rat Liver
DOSE/DURATION : 1 mg/L
REFERENCE :
CNREA8 Cancer Research. (Public Ledger Building, Suit 816, 6th & Chestnut
Sts., Philadelphia, PA 19106) V.1- 1941- Volume(issue)/page/year:
44,5599,1984
TYPE OF TEST : DNA inhibition
TEST SYSTEM : Rodent - mouse Fibroblast
DOSE/DURATION : 1 umol/L
REFERENCE :
CNREA8 Cancer Research. (Public Ledger Building, Suit 816, 6th & Chestnut
Sts., Philadelphia, PA 19106) V.1- 1941- Volume(issue)/page/year:
37,4523,1977
*** END OF RECORD ***