*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : QI9457550
CHEMICAL NAME           : 5(8H)-Naphthacenone,
                          7,9,10,12-tetrahydro-8-acetyl-10-((3-(3-cyano-4-morph
                          olinyl)-2,3,6-
                          trideoxy-alpha-L-lyxo-hexopyranosyl)oxy)-8-(hydroxyac
                          etyl)-12-imino-1-meth oxy-6,8,11- trihydroxy-,
                          (8S-cis)-
LAST UPDATED            : 199409
DATA ITEMS CITED        : 5
MOLECULAR FORMULA       : C32-H34-N3-O11
MOLECULAR WEIGHT        : 636.69
COMPOUND DESCRIPTOR     : Mutagen
SYNONYMS/TRADE NAMES :
   * 5-Imino-3'-(3-cyano-4-morpholinyl)-3'-deaminoadriamycin
 
                       *** HEALTH HAZARD DATA ***
 
                            ** MUTATION DATA **
 
TYPE OF TEST            : DNA damage
TEST SYSTEM             : Microorganism - not otherwise specified
DOSE/DURATION           : 50 umol/L
REFERENCE :
   CNREA8 Cancer Research. (Public Ledger Building, Suit 816, 6th & Chestnut
   Sts., Philadelphia, PA 19106)  V.1-    1941-  Volume(issue)/page/year:
   49,7031,1989
 
TYPE OF TEST            : DNA damage
TEST SYSTEM             : Human Cells - not otherwise specified
DOSE/DURATION           : 20 umol/L
REFERENCE :
   PAACA3 Proceedings of the American Association for Cancer Research. (Waverly
   Press, 428 E. Preston St., Baltimore, MD 21202)  V.1-    1954-
   Volume(issue)/page/year: 27,251,1986
 
TYPE OF TEST            : DNA damage
TEST SYSTEM             : Human Lymphocyte
DOSE/DURATION           : 500 nmol/L
REFERENCE :
   CNREA8 Cancer Research. (Public Ledger Building, Suit 816, 6th & Chestnut
   Sts., Philadelphia, PA 19106)  V.1-    1941-  Volume(issue)/page/year:
   49,7031,1989
 
TYPE OF TEST            : DNA inhibition
TEST SYSTEM             : Human Cells - not otherwise specified
DOSE/DURATION           : 30 nmol/L/2H
REFERENCE :
   CNREA8 Cancer Research. (Public Ledger Building, Suit 816, 6th & Chestnut
   Sts., Philadelphia, PA 19106)  V.1-    1941-  Volume(issue)/page/year:
   47,4076,1987
 
TYPE OF TEST            : Mutation test systems - not otherwise specified
TEST SYSTEM             : Human Cells - not otherwise specified
DOSE/DURATION           : 4 nmol/L/2H
REFERENCE :
   CNREA8 Cancer Research. (Public Ledger Building, Suit 816, 6th & Chestnut
   Sts., Philadelphia, PA 19106)  V.1-    1941-  Volume(issue)/page/year:
   47,4076,1987
 
                            *** END OF RECORD ***