*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : QJ0875000
CHEMICAL NAME           : 1-Naphthaleneacetic acid
CAS REGISTRY NUMBER     : 86-87-3
OTHER CAS REGISTRY NOS. : 61913-11-9
LAST UPDATED            : 199710
DATA ITEMS CITED        : 17
MOLECULAR FORMULA       : C12-H10-O2
MOLECULAR WEIGHT        : 186.22
WISWESSER LINE NOTATION : L66J B1VQ
COMPOUND DESCRIPTOR     : Agricultural Chemical
                          Mutagen
                          Primary Irritant
SYNONYMS/TRADE NAMES :
   * Acide naphthylacetique
   * Agronaa
   * Alman
   * Alphaspra
   * ANU
   * Appl-set
   * Biokor
   * Celmone
   * Fruitofix
   * Fruitone N
   * Kyselina 1-naftyloctova
   * Klingtite
   * Liqui-stik
   * NAA
   * alpha-Naa
   * 1-NAA
   * NAA 800
   * Nafusaku
   * Naphthaleneacetic acid
   * Naphthalene-1-acetic acid
   * alpha-Naphthaleneacetic acid
   * alpha-Naphthylacetic
   * Naphthylacetic acid
   * alpha-Naphthylacetic acid
   * 1-Naphthylacetic acid
   * 2-(1-Naphthyl)acetic acid
   * alpha-Naphthyleneacetic acid
   * alpha-Naphthylessigsaeure
   * Naphyl-1-essigsaeure
   * Niagara-stik
   * NU-Tone
   * Phyomone
   * Pimacol-sol
   * Planofix
   * Planofixe
   * Plucker
   * Pomoxon
   * Primacol
   * Rasin
   * Rhodofix
   * Stafast
   * STIK
   * Stop-Drop
   * Tekkam
   * Tip-Off
   * Transplantone
   * Tre-Hold
   * Vardhak
 
                       *** HEALTH HAZARD DATA ***
 
                      ** SKIN/EYE IRRITATION DATA **
 
TYPE OF TEST            : Standard Draize test
ROUTE OF EXPOSURE       : Administration into the eye
SPECIES OBSERVED        : Rodent - rabbit
DOSE/DURATION           : 100 mg
REACTION SEVERITY       : Severe
REFERENCE :
   PESTC* Pesticide & Toxic Chemical News.  (Food Chemical News, Inc., 400
   Wyatt Bldg., 777 14th St., NW, Washington, DC 20005)  V.1-    1972-
   Volume(issue)/page/year: 9,10,1980
 
                        ** ACUTE TOXICITY DATA **
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : 1 gm/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   85DPAN "Wirksubstanzen der Pflanzenschutz und Schadlingsbekampfungsmittel,"
   Perkow, W., Berlin, Verlag Paul Parey, 1971-1976  Volume(issue)/page/year:
   -,-,1971/1976
 
TYPE OF TEST            : LC50 - Lethal concentration, 50 percent kill
ROUTE OF EXPOSURE       : Inhalation
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : >207 gm/m3
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   PESTC* Pesticide & Toxic Chemical News.  (Food Chemical News, Inc., 400
   Wyatt Bldg., 777 14th St., NW, Washington, DC 20005)  V.1-    1972-
   Volume(issue)/page/year: 9,10,1980
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intraperitoneal
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : 100 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   PESTC* Pesticide & Toxic Chemical News.  (Food Chemical News, Inc., 400
   Wyatt Bldg., 777 14th St., NW, Washington, DC 20005)  V.1-    1972-
   Volume(issue)/page/year: 9,10,1980
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 743 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   TOIZAG Toho Igakkai Zasshi.  Journal of Medical Society of Toho University.
   (Toho Daigaku Igakkai, 21-16, Omori-nishi, 5-chome, Ota-ku, Tokyo 143,
   Japan)  V.1-    1954-  Volume(issue)/page/year: 14,132,1967
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intraperitoneal
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 609 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   TOIZAG Toho Igakkai Zasshi.  Journal of Medical Society of Toho University.
   (Toho Daigaku Igakkai, 21-16, Omori-nishi, 5-chome, Ota-ku, Tokyo 143,
   Japan)  V.1-    1954-  Volume(issue)/page/year: 15,443,1968
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Subcutaneous
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 733 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   TOIZAG Toho Igakkai Zasshi.  Journal of Medical Society of Toho University.
   (Toho Daigaku Igakkai, 21-16, Omori-nishi, 5-chome, Ota-ku, Tokyo 143,
   Japan)  V.1-    1954-  Volume(issue)/page/year: 15,443,1968
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Administration onto the skin
SPECIES OBSERVED        : Rodent - rabbit
DOSE/DURATION           : >5 gm/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   PEMNDP Pesticide Manual.  (The British Crop Protection Council, 20 Bridport
   Rd., Thornton Heath CR4 7QG, UK)  V.1-    1968-  Volume(issue)/page/year:
   9,607,1991
 
                 ** OTHER MULTIPLE DOSE TOXICITY DATA **
 
TYPE OF TEST            : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : 27 gm/kg/90D-C
TOXIC EFFECTS :
   Behavioral - food intake (animal)
   Liver - changes in liver weight
   Nutritional and Gross Metabolic - weight loss or decreased weight gain
REFERENCE :
   TXCYAC Toxicology.  (Elsevier Scientific Pub. Ireland, Ltd., POB 85,
   Limerick, Ireland) V.1-    1973-  Volume(issue)/page/year: 5,371,1976
 
TYPE OF TEST            : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : 30 gm/kg/30D-I
TOXIC EFFECTS :
   Liver - changes in liver weight
   Blood - pigmented or nucleated red blood cells
   Nutritional and Gross Metabolic - weight loss or decreased weight gain
REFERENCE :
   GISAAA Gigiena i Sanitariya.  For English translation, see HYSAAV.  (V/O
   Mezhdunarodnaya Kniga, 113095 Moscow, USSR)  V.1-    1936-
   Volume(issue)/page/year: 55(4),93,1990
 
                            ** MUTATION DATA **
 
TYPE OF TEST            : Mutation in microorganisms
TEST SYSTEM             : Yeast - Saccharomyces cerevisiae
DOSE/DURATION           : 500 mg/L
REFERENCE :
   IDZAAW Japanese Journal of Genetics.  Idengaku Zasshi.  (Genetics Soc. of
   Japan, 111 Tanida, Mishima, Shizuoka-ken, Japan)  V.1-    1921-
   Volume(issue)/page/year: 48,185,1973
 
TYPE OF TEST            : Mutation test systems - not otherwise specified
TEST SYSTEM             : Human Leukocyte
DOSE/DURATION           : 100 nmol/L
REFERENCE :
   EXPEAM Experientia.  (Birkhaeuser Verlag, POB 133, CH-4010 Basel,
   Switzerland)  V.1-    1945-  Volume(issue)/page/year: 32,29,1976

                    *** U.S. STANDARDS AND REGULATIONS ***
 
   EPA FIFRA 1988 PESTICIDE SUBJECT TO REGISTRATION OR RE-REGISTRATION
   FEREAC Federal Register.  (U.S. Government Printing Office, Supt. of
   Documents, Washington, DC 20402) V.1-    1936-  Volume(issue)/page/year:
   54,7740,1989

         *** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA ***

NIOSH OCCUPATIONAL EXPOSURE SURVEY DATA :
   NOHS - National Occupational Hazard Survey (1974)
     NOHS Hazard Code - 80317
       No. of Facilities: 43 (estimated)
       No. of Industries: 1
       No. of Occupations: 8
       No. of Employees: 605 (estimated)
   
   NOES - National Occupational Exposure Survey (1983)
     NOES Hazard Code - 80317
       No. of Facilities: 287 (estimated)
       No. of Industries: 1
       No. of Occupations: 1
       No. of Employees: 3732 (estimated)
       No. of Female Employees: 574 (estimated)

                          *** STATUS IN U.S. ***
 
   EPA TSCA Section 8(b) CHEMICAL INVENTORY
   
   EPA TSCA TEST SUBMISSION (TSCATS) DATA BASE, JUNE 1998

 
                            *** END OF RECORD ***