*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : BC8055000
CHEMICAL NAME           : Aloe, pharmaceutical
CAS REGISTRY NUMBER     : 8001-97-6
LAST UPDATED            : 199509
DATA ITEMS CITED        : 6
COMPOUND DESCRIPTOR     : Drug
                          Mutagen
                          Natural Product
SYNONYMS/TRADE NAMES :
   * Aloe (Latin)
   * Aloe, powdered
   * AROE
 
                       *** HEALTH HAZARD DATA ***
 
                        ** ACUTE TOXICITY DATA **
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : >5 gm/kg
TOXIC EFFECTS :
   Behavioral - somnolence (general depressed activity)
   Gastrointestinal - hypermotility, diarrhea
   Skin and Appendages - hair
REFERENCE :
   KSRNAM Kiso to Rinsho.  Clinical Report.  (Yubunsha Co., Ltd., 1-5, Kanda
   Suda-Cho, Chiyoda-ku, KS Bldg., Tokyo 101, Japan)  V.1-    1960-
   Volume(issue)/page/year: 14,1403,1980
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : >10 gm/kg
TOXIC EFFECTS :
   Behavioral - somnolence (general depressed activity)
   Gastrointestinal - hypermotility, diarrhea
   Skin and Appendages - hair
REFERENCE :
   KSRNAM Kiso to Rinsho.  Clinical Report.  (Yubunsha Co., Ltd., 1-5, Kanda
   Suda-Cho, Chiyoda-ku, KS Bldg., Tokyo 101, Japan)  V.1-    1960-
   Volume(issue)/page/year: 14,1403,1980
 
                            ** MUTATION DATA **
 
TYPE OF TEST            : DNA repair
TEST SYSTEM             : Bacteria - Bacillus subtilis
DOSE/DURATION           : 100 gm/L
REFERENCE :
   MUREAV Mutation Research.  (Elsevier Science Pub. B.V., POB 211, 1000 AE
   Amsterdam, Netherlands) V.1-    1964-  Volume(issue)/page/year: 97,81,1982

         *** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA ***

NIOSH OCCUPATIONAL EXPOSURE SURVEY DATA :
   NOHS - National Occupational Hazard Survey (1974)
     NOHS Hazard Code - M1046
       No. of Facilities: 88 (estimated)
       No. of Industries: 2
       No. of Occupations: 6
       No. of Employees: 1238 (estimated)
   
   NOES - National Occupational Exposure Survey (1983)
     NOES Hazard Code - M1046
       No. of Facilities: 1400 (estimated)
       No. of Industries: 3
       No. of Occupations: 12
       No. of Employees: 30874 (estimated)
       No. of Female Employees: 23491 (estimated)
   
   NOES - National Occupational Exposure Survey (1983)
     NOES Hazard Code - X9856
       No. of Facilities: 6 (estimated)
       No. of Industries: 1
       No. of Occupations: 1
       No. of Employees: 42 (estimated)
       No. of Female Employees: 18 (estimated)

 
                            *** END OF RECORD ***