*** CHEMICAL IDENTIFICATION ***
RTECS NUMBER : BD0940000
CHEMICAL NAME : Aluminum hydroxide (Al(OH)3)
CAS REGISTRY NUMBER : 21645-51-2
OTHER CAS REGISTRY NOS. : 1302-29-0
12252-70-9
51330-22-4
LAST UPDATED : 199712
DATA ITEMS CITED : 26
MOLECULAR FORMULA : Al-H3-O3
MOLECULAR WEIGHT : 78.01
WISWESSER LINE NOTATION : .AL..H3.O3
COMPOUND DESCRIPTOR : Drug
Human
SYNONYMS/TRADE NAMES :
* AF 260
* Alcoa 331
* Alcoa C 30BF
* Alumigel
* Alumina hydrated
* Alumina trihydrate
* alpha-Alumina trihydrate
* Aluminic acid
* Aluminium hydroxide
* Aluminum hydrate
* Aluminum(III) hydroxide
* Aluminum hydroxide gel
* Aluminum oxide trihydrate
* Aluminum trihydrate
* Aluminum trihydroxide
* Alusal
* Amberol ST 140F
* Amphojel
* BACO AF 260
* British aluminum AF 260
* C 31
* C 33
* C 31C
* C 4D
* C 31F
* C-31-F
* C.I. 77002
* GHA 331
* GHA 332
* H 46
* Higilite
* Higilite H 32
* Higilite H 42
* Higilite H 31S
* Hychol 705
* Hydral 705
* Hydral 710
* Hydrated alumina
* Liquigel
* Martinal
* P 30BF
* PGA
* Trihydrated alumina
* Trihydroxyaluminum
*** HEALTH HAZARD DATA ***
** ACUTE TOXICITY DATA **
TYPE OF TEST : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE : Oral
SPECIES OBSERVED : Human - child
DOSE/DURATION : 79 gm/kg/2Y-I
TOXIC EFFECTS :
Behavioral - changes in motor activity (specific assay)
Behavioral - muscle contraction or spasticity
Musculoskeletal - osteomalacia
REFERENCE :
PEDIAU Pediatrics. (American Academy of Pediatrics, P.O. Box 1034,
Evanston, IL 60204) V.1- 1948- Volume(issue)/page/year: 71,56,1983
TYPE OF TEST : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE : Oral
SPECIES OBSERVED : Human - child
DOSE/DURATION : 122 gm/kg/4D
TOXIC EFFECTS :
Gastrointestinal - other changes
Nutritional and Gross Metabolic - body temperature increase
REFERENCE :
JOPDAB Journal of Pediatrics. (C.V. Mosby Co., 11830 Westline Industrial
Dr., St. Louis, MO 63141) V.1- 1932- Volume(issue)/page/year:
92,592,1978
TYPE OF TEST : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE : Unreported
SPECIES OBSERVED : Human - infant
DOSE/DURATION : 39 gm/kg/24D-I
TOXIC EFFECTS :
Musculoskeletal - osteomalacia
REFERENCE :
NEJMAG New England Journal of Medicine. (Massachusetts Medical Soc., 10
Shattuck St., Boston, MA 02115) V.198- 1928- Volume(issue)/page/year:
310,1079,1984
TYPE OF TEST : LDLo - Lowest published lethal dose
ROUTE OF EXPOSURE : Intraperitoneal
SPECIES OBSERVED : Rodent - rat
DOSE/DURATION : 150 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
LANCAO Lancet. (7 Adam St., London WC2N 6AD, UK) V.1- 1823-
Volume(issue)/page/year: 1,564,1972
** OTHER MULTIPLE DOSE TOXICITY DATA **
TYPE OF TEST : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE : Oral
SPECIES OBSERVED : Rodent - rat
DOSE/DURATION : 8040 mg/kg/67D-C
TOXIC EFFECTS :
Blood - changes in serum composition (e.g. TP, bilirubin, cholesterol)
Nutritional and Gross Metabolic - changes in phosphorus
REFERENCE :
FAATDF Fundamental and Applied Toxicology. (Academic Press, Inc., 1 E.
First St., Duluth, MN 55802) V.1- 1981- Volume(issue)/page/year:
10,616,1988
*** REVIEWS ***
ACGIH TLV-TWA 2 mg(Al)/m3
DTLVS* The Threshold Limit Values (TLVs) and Biological Exposure Indices
(BEIs) booklet issues by American Conference of Governmental Industrial
Hygienists (ACGIH), Cincinnati, OH, 1996 Volume(issue)/page/year:
TLV/BEI,1997
*** OCCUPATIONAL EXPOSURE LIMITS ***
OEL-AUSTRALIA:TWA 2 mg(Al)/m3 JAN 1993
OEL-BELGIUM:TWA 2 mg(Al)/m3 JAN 1993
OEL-DENMARK:TWA 2 mg(Al)/m3 JAN 1993
OEL-FRANCE:TWA 2 mg(Al)/m3 JAN 1993
OEL-GERMANY:TWA 6 mg/m3 JAN 1993
OEL-THE NETHERLANDS:TWA 2 mg(Al)/m3 JAN 1993
OEL-RUSSIA:STEL 6 mg/m3 JAN 1993
OEL-RUSSIA:TWA 2 mg(Al)/m3 JAN 1993
OEL-SWEDEN:TWA 2 mg(Al)/m3 JAN 1993
OEL-SWITZERLAND:TWA 2 mg(Al)/m3 JAN 1993
OEL-SWITZERLAND:TWA 6 mg/m3 JAN 1993
OEL-UNITED KINGDOM:TWA 2 mg(Al)/m3 JAN 1993
OEL IN BULGARIA, COLOMBIA, JORDAN, KOREA check ACGIH TLV
OEL IN NEW ZEALAND, SINGAPORE, VIETNAM check ACGIH TLV
*** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA ***
NIOSH OCCUPATIONAL EXPOSURE SURVEY DATA :
NOHS - National Occupational Hazard Survey (1974)
NOHS Hazard Code - 80390
No. of Facilities: 4981 (estimated)
No. of Industries: 85
No. of Occupations: 74
No. of Employees: 97261 (estimated)
NOES - National Occupational Exposure Survey (1983)
NOES Hazard Code - X4445
No. of Facilities: 297 (estimated)
No. of Industries: 2
No. of Occupations: 8
No. of Employees: 37773 (estimated)
No. of Female Employees: 33522 (estimated)
NOES - National Occupational Exposure Survey (1983)
NOES Hazard Code - X9931
No. of Facilities: 59 (estimated)
No. of Industries: 1
No. of Occupations: 4
No. of Employees: 7006 (estimated)
No. of Female Employees: 6697 (estimated)
NOES - National Occupational Exposure Survey (1983)
NOES Hazard Code - 80390
No. of Facilities: 12057 (estimated)
No. of Industries: 123
No. of Occupations: 121
No. of Employees: 325788 (estimated)
No. of Female Employees: 84539 (estimated)
*** STATUS IN U.S. ***
EPA TSCA Section 8(b) CHEMICAL INVENTORY
EPA TSCA TEST SUBMISSION (TSCATS) DATA BASE, JUNE 1998
*** END OF RECORD ***