*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : BD9635000
CHEMICAL NAME           : 10-alpha-H-Ambrosa-2,11(13)-dien-12-oic acid,
                          1,6-beta-dihydroxy-4-oxo-, gamma-lactone
CAS REGISTRY NUMBER     : 508-59-8
LAST UPDATED            : 198608
DATA ITEMS CITED        : 4
MOLECULAR FORMULA       : C15-H18-O4
MOLECULAR WEIGHT        : 262.33
WISWESSER LINE NOTATION : T B575 COVY MV KUTJ A1 EU1 I1 JQ
COMPOUND DESCRIPTOR     : Mutagen
                          Natural Product
SYNONYMS/TRADE NAMES :
   * Parthenicin
   * Parthenin
 
                       *** HEALTH HAZARD DATA ***
 
                        ** ACUTE TOXICITY DATA **
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intraperitoneal
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : 42 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   JOBSDN Journal of Biosciences.  (Indian Academy of Sciences, POB 8005,
   Bangalore 560080, India) V.1-    1979-  Volume(issue)/page/year: 6,729,1984
 
                            ** MUTATION DATA **
 
TYPE OF TEST            : Cytogenetic analysis
TEST SYSTEM             : Human Leukocyte
DOSE/DURATION           : 1 nmol/L
REFERENCE :
   IJEBA6 Indian Journal of Experimental Biology.  (Publications & Information
   Directorate, CSIR, Hillside Rd., New Delhi 110 012, India)  V.1-    1963-
   Volume(issue)/page/year: 16,1117,1978
 
TYPE OF TEST            : Micronucleus test
ROUTE OF EXPOSURE       : Intraperitoneal
TEST SYSTEM             : Rodent - mouse
DOSE/DURATION           : 200 mg/kg/24H (Intermittent)
REFERENCE :
   IJEBA6 Indian Journal of Experimental Biology.  (Publications & Information
   Directorate, CSIR, Hillside Rd., New Delhi 110 012, India)  V.1-    1963-
   Volume(issue)/page/year: 16,1117,1978
 
TYPE OF TEST            : Cytogenetic analysis
TEST SYSTEM             : Rodent - hamster Ovary
DOSE/DURATION           : 3120 ppb
REFERENCE :
   BSECBU Biochemical Systematics and Ecology.  (Pergamon Press Inc., Maxwell
   House, Fairview Park, Elmsford, NY 10523)  V.2-     1974-
   Volume(issue)/page/year: 13,365,1985
 
                            *** END OF RECORD ***