*** CHEMICAL IDENTIFICATION *** RTECS NUMBER : BO3675000 CHEMICAL NAME : Ammonium, N-alkyl(C9-15)tolyl methyltrimethyl-, chloride CAS REGISTRY NUMBER : 1399-80-0 LAST UPDATED : 199606 DATA ITEMS CITED : 8 COMPOUND DESCRIPTOR : Agricultural Chemical Primary Irritant SYNONYMS/TRADE NAMES : * Alkyl(C9-15)tolyl methyltrimethyl ammonium chloride * Dodecyl p-tolyl trimethyl ammonium chloride * Hyamine 2389 * Methyl dodecyl benzyl ammonium chloride *** HEALTH HAZARD DATA *** ** SKIN/EYE IRRITATION DATA ** TYPE OF TEST : Standard Draize test ROUTE OF EXPOSURE : Administration onto the skin SPECIES OBSERVED : Human - man DOSE/DURATION : 50 mg/2D REACTION SEVERITY : Mild REFERENCE : PSTGAW Proceedings of the Scientific Section of the Toilet Goods Association. (Washington, DC) No.1-48, 1944-67. Discontinued. Volume(issue)/page/year: 20,16,1953 TYPE OF TEST : Standard Draize test ROUTE OF EXPOSURE : Administration into the eye SPECIES OBSERVED : Rodent - rabbit DOSE/DURATION : 100 ug REACTION SEVERITY : Severe REFERENCE : PSTGAW Proceedings of the Scientific Section of the Toilet Goods Association. (Washington, DC) No.1-48, 1944-67. Discontinued. Volume(issue)/page/year: 20,16,1953 ** ACUTE TOXICITY DATA ** TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Oral SPECIES OBSERVED : Rodent - rat DOSE/DURATION : 389 mg/kg TOXIC EFFECTS : Details of toxic effects not reported other than lethal dose value REFERENCE : JPETAB Journal of Pharmacology and Experimental Therapeutics. (Williams & Wilkins Co., 428 E. Preston St., Baltimore, MD 21202) V.1- 1909/10- Volume(issue)/page/year: 109,422,1953 TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Intraperitoneal SPECIES OBSERVED : Rodent - rat DOSE/DURATION : 10 mg/kg TOXIC EFFECTS : Details of toxic effects not reported other than lethal dose value REFERENCE : AEHA** U.S. Army, Environmental Hygiene Agency Reports. (Edgewood Arsenal, MD 21010) Volume(issue)/page/year: 5176T6-66/1967 TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Intravenous SPECIES OBSERVED : Rodent - rat DOSE/DURATION : 3060 ug/kg TOXIC EFFECTS : Details of toxic effects not reported other than lethal dose value REFERENCE : JPETAB Journal of Pharmacology and Experimental Therapeutics. (Williams & Wilkins Co., 428 E. Preston St., Baltimore, MD 21202) V.1- 1909/10- Volume(issue)/page/year: 109,422,1953 ** OTHER MULTIPLE DOSE TOXICITY DATA ** TYPE OF TEST : TDLo - Lowest published toxic dose ROUTE OF EXPOSURE : Oral SPECIES OBSERVED : Rodent - rat DOSE/DURATION : 91 mg/kg/2Y-C TOXIC EFFECTS : Gastrointestinal - other changes Nutritional and Gross Metabolic - weight loss or decreased weight gain Related to Chronic Data - death REFERENCE : JPETAB Journal of Pharmacology and Experimental Therapeutics. (Williams & Wilkins Co., 428 E. Preston St., Baltimore, MD 21202) V.1- 1909/10- Volume(issue)/page/year: 109,422,1953 *** REVIEWS *** TOXICOLOGY REVIEW SCHSAV Soap and Chemical Specialties. (New York, NY) V.30-47, 1954-71. For publisher information, see SCCSC8. Volume(issue)/page/year: 30,147,1954 *** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA *** NIOSH OCCUPATIONAL EXPOSURE SURVEY DATA : NOES - National Occupational Exposure Survey (1983) NOES Hazard Code - X9193 No. of Facilities: 46 (estimated) No. of Industries: 1 No. of Occupations: 1 No. of Employees: 46 (estimated) No. of Female Employees: 46 (estimated) *** END OF RECORD ***