*** CHEMICAL IDENTIFICATION *** RTECS NUMBER : AY7650000 CHEMICAL NAME : Alanine, 3-(3,4,6-trihydroxyphenyl)-2-methyl-, DL- CAS REGISTRY NUMBER : 65520-36-7 LAST UPDATED : 198609 DATA ITEMS CITED : 1 MOLECULAR FORMULA : C10-H13-N-O5 MOLECULAR WEIGHT : 227.24 WISWESSER LINE NOTATION : QVXZ1&1R BQ DQ EQ COMPOUND DESCRIPTOR : Drug SYNONYMS/TRADE NAMES : * Alanine, 2-methyl-3-(3,4,6-trihydroxyphenyl)-, DL- * (RS)-6-Hydroxy-alpha-methyldopa *** HEALTH HAZARD DATA *** ** ACUTE TOXICITY DATA ** TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Intraperitoneal SPECIES OBSERVED : Rodent - mouse DOSE/DURATION : 289 mg/kg TOXIC EFFECTS : Liver - hepatitis (hepatocellular necrosis), diffuse Kidney, Ureter, Bladder - changes in tubules (including acute renal failure, acute tubular necrosis) REFERENCE : JMCMAR Journal of Medicinal Chemistry. (American Chemical Soc., Distribution Office Dept. 223, POB POB 57136, West End Stn., Washington, DC 20037) V.6- 1963- Volume(issue)/page/year: 23,1318,1980 *** END OF RECORD ***