*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : AY7650000
CHEMICAL NAME           : Alanine, 3-(3,4,6-trihydroxyphenyl)-2-methyl-, DL-
CAS REGISTRY NUMBER     : 65520-36-7
LAST UPDATED            : 198609
DATA ITEMS CITED        : 1
MOLECULAR FORMULA       : C10-H13-N-O5
MOLECULAR WEIGHT        : 227.24
WISWESSER LINE NOTATION : QVXZ1&1R BQ DQ EQ
COMPOUND DESCRIPTOR     : Drug
SYNONYMS/TRADE NAMES :
   * Alanine, 2-methyl-3-(3,4,6-trihydroxyphenyl)-, DL-
   * (RS)-6-Hydroxy-alpha-methyldopa
 
                       *** HEALTH HAZARD DATA ***
 
                        ** ACUTE TOXICITY DATA **
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intraperitoneal
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 289 mg/kg
TOXIC EFFECTS :
   Liver - hepatitis (hepatocellular necrosis), diffuse
   Kidney, Ureter, Bladder - changes in tubules (including acute renal failure,
   acute tubular necrosis)
REFERENCE :
   JMCMAR Journal of Medicinal Chemistry.  (American Chemical Soc.,
   Distribution Office Dept. 223, POB POB 57136, West End Stn., Washington, DC
   20037)  V.6-    1963-  Volume(issue)/page/year: 23,1318,1980
 
                            *** END OF RECORD ***