*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : AZ5820000
CHEMICAL NAME           : Alginic acid, sodium salt
CAS REGISTRY NUMBER     : 9005-38-3
OTHER CAS REGISTRY NOS. : 9005-40-7
LAST UPDATED            : 199701
DATA ITEMS CITED        : 9
COMPOUND DESCRIPTOR     : Drug
SYNONYMS/TRADE NAMES :
   * Algin
   * Algin (polysaccharide)
   * Alginate KMF
   * Algipon L-1168
   * Amnucol
   * Antimigrant C 45
   * Cecalgine TBV
   * Cohasal-IH
   * Darid QH
   * Dariloid QH
   * Duckalgin
   * Halltex
   * Kelco Gel LV
   * Kelcosol
   * Kelgin
   * Kelgin F
   * Kelgin HV
   * Kelgin LV
   * Kelgin XL
   * Kelgum
   * Kelset
   * Kelsize
   * Keltex
   * Keltone
   * Algiline
   * Lamitex
   * Manucol
   * Manucol DM
   * Manucol KMF
   * Manucol SS/LD2
   * Manugel F 331
   * Manutex
   * Manutex F
   * Manutex RS
   * Manutex RS 1
   * Manutex RS-5
   * Manutex SA/KP
   * Manutex SH/LH
   * Meypralgin R/LV
   * Minus
   * Mosanon
   * Nouralgine
   * OG 1
   * Pectalgine
   * Proctin
   * Protacell 8
   * Protanal
   * Protatek
   * Snow algin H
   * Snow algin L
   * Snow algin M
   * Sodium alginate
   * Sodium polymannuronate
   * Stipine
   * Tagat
   * Tragaya
 
                       *** HEALTH HAZARD DATA ***
 
                        ** ACUTE TOXICITY DATA **
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : >5 gm/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   NIIRDN Drugs in Japan (Ethical Drugs).  (Yakugyo Jiho Co., Ltd., Tokyo,
   Japan)  Volume(issue)/page/year: 6,42,1982
 
TYPE OF TEST            : LD - Lethal dose
ROUTE OF EXPOSURE       : Intraperitoneal
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : >1 gm/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   IJPPAZ Indian Journal of Physiology and Pharmacology.  (All India Institute
   of Medical Sciences, Dept. of Physiology, Ansari Nagar, New Delhi 110 029,
   India)  V.1-    1957-  Volume(issue)/page/year: 12,129,1968
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intravenous
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : 1 gm/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   FAONAU FAO Nutrition Meetings Report Series.  (Rome, Italy)  No.?-57,
   1948-77.  Discontinued.  Volume(issue)/page/year: 53A,381,1974
 
TYPE OF TEST            : LDLo - Lowest published lethal dose
ROUTE OF EXPOSURE       : Intraperitoneal
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 500 mg/kg
TOXIC EFFECTS :
   Blood - hemorrhage
REFERENCE :
   IJPPAZ Indian Journal of Physiology and Pharmacology.  (All India Institute
   of Medical Sciences, Dept. of Physiology, Ansari Nagar, New Delhi 110 029,
   India)  V.1-    1957-  Volume(issue)/page/year: 12,129,1968
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intraperitoneal
SPECIES OBSERVED        : Mammal - cat
DOSE/DURATION           : 250 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   FAONAU FAO Nutrition Meetings Report Series.  (Rome, Italy)  No.?-57,
   1948-77.  Discontinued.  Volume(issue)/page/year: 53A,381,1974
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intravenous
SPECIES OBSERVED        : Rodent - rabbit
DOSE/DURATION           : 100 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   FAONAU FAO Nutrition Meetings Report Series.  (Rome, Italy)  No.?-57,
   1948-77.  Discontinued.  Volume(issue)/page/year: 53A,381,1974

         *** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA ***

NIOSH OCCUPATIONAL EXPOSURE SURVEY DATA :
   NOHS - National Occupational Hazard Survey (1974)
     NOHS Hazard Code - 80439
       No. of Facilities: 1972 (estimated)
       No. of Industries: 29
       No. of Occupations: 35
       No. of Employees: 73822 (estimated)
   
   NOES - National Occupational Exposure Survey (1983)
     NOES Hazard Code - 80439
       No. of Facilities: 5135 (estimated)
       No. of Industries: 67
       No. of Occupations: 51
       No. of Employees: 106305 (estimated)
       No. of Female Employees: 35825 (estimated)

                          *** STATUS IN U.S. ***
 
   EPA TSCA Section 8(b) CHEMICAL INVENTORY

 
                            *** END OF RECORD ***